Is partial cystectomy the treatment of choice for mucinous adenocarcinoma of the urachus?

• Published in: Urology (Ridgewood, N.J.) Vol. 49; no. 4; pp. 536 - 540
• Main Authors: Santucci, Richard A., True, Lawrence D., Lange, Paul H.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.04.1997; Elsevier Science
• Subjects: Adenocarcinoma, Mucinous - surgery; Aged; Biological and medical sciences; Cystectomy - methods; Female; Humans; Medical sciences; Retrospective Studies; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the urinary system; Urachus - surgery; Human; Urinary system disease; Prognosis; Exploration; Histology; Malignant tumor; Survival; Pathology; Cystectomy; Treatment; Partial; Surgery; Urachus; Mucinous adenocarcinoma
• ISSN: 0090-4295; 1527-9995
• DOI: 10.1016/S0090-4295(96)00574-2

Objectives. To determine if well-differentiated colonic-type adenocarcinoma of the urachus behaves in a benign fashion, and thus might be treated by segmental rather than radical cystectomy. Methods. A retrospective review of the literature since 1863 with one added case review is presented here. Only cases with photomicrograph confirmation were accepted. Results. Sixteen previously reported patients with well-differentiated colonic-type adenocarcinoma of the urachus were treated by partial cystectomy. None were treated by radical cystectomy. Most (88%) of these patients were cured, whereas all patients (100%) treated in the last 45 years were cured. Conclusions. These data support a more limited approach to the surgical excision of these benign-appearing tumors. The influence of this histologic type on the prognosis of patients with urachal tumors has not been previously reported.