Effects of dopamine and opioid receptor antagonism on the neural processing of social and nonsocial rewards

• Published in: Human brain mapping Vol. 45; no. 4; pp. e26645 - n/a
• Main Authors: Massaccesi, Claudia, Korb, Sebastian, Götzendorfer, Sebastian, Chiappini, Emilio, Willeit, Matthaeus, Lundström, Johan N., Windischberger, Christian, Eisenegger, Christoph, Silani, Giorgia
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.03.2024
• Subjects: Anatomy; Animal research; Animals; Approach behavior; Blindness; Brain; Brain architecture; Brain research; Dopamine; Dopamine receptors; Drug development; Emotions; fMRI; Food; Humans; Information processing; Magnetic resonance imaging; Medical imaging; Milk; Motivation; Naltrexone; Narcotic Antagonists - pharmacology; Narcotics; Neurochemistry; Neuroimaging; Opioid receptors; opioids; Placebos; Receptors, Opioid; Reinforcement; reward; social touch; Touch; reward; social touch; fMRI; dopamine; food; opioids

Rewards are a broad category of stimuli inducing approach behavior to aid survival. Extensive evidence from animal research has shown that wanting (the motivation to pursue a reward) and liking (the pleasure associated with its consumption) are mostly regulated by dopaminergic and opioidergic activi...