THE SELECTION BARRIER BETWEEN POPULATIONS SUBJECT TO STABILIZING SELECTION

• Published in: Evolution Vol. 49; no. 3; p. 490
• Main Authors: Zhivotovsky, Lev A, Christiansen, Freddy Bugge
• Format: Journal Article
• Language: English
• Published: United States 01.06.1995
• Subjects: multiple loci; introgression; selection barrier; stabilizing selection; postzygotic isolation mechanisms; Genetic barrier
• ISSN: 1558-5646
• DOI: 10.1111/j.1558-5646.1995.tb02281.x

The introgression of genes carried by a small group of immigrants is studied. The recipient and the donor populations differ at several autosomal loci subject to weak selection, and two allelic forms of each gene are considered. Fitness variation is determined by additive allelic effects, by dominance effects, and by two-locus additive-by-additive epistatic interaction of the effects of the alleles. The fate of the group of immigrants is quantified by the selection barrier that describes the cumulative mean fitness of the hybrids and hybrid descendants relative to the fitness of the resident population. The monomorphic and the polymorphic loci of the recipient population contribute differently to the selection barrier. If the genetic difference between recipient and donor population is small, then the contribution of the monomorphic loci is dominated by a positive term dependent on the difference in gene frequencies. The contribution of the polymorphic loci depends only on the difference of the leading order in the pairwise linkage disequilibria between the two populations. This contribution may be positive or negative; and, thus, polymorphic loci may either contribute to the barrier or inflate the introgression.