Customized spatial niches for synthetic microbial consortia

• Published in: Trends in biotechnology (Regular ed.) Vol. 41; no. 12; pp. 1463 - 1466
• Main Authors: Gao, Hao, Jiang, Wankui, Zhang, Wenming, Jiang, Min, Xin, Fengxue
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.12.2023; Elsevier Limited
• Subjects: Additive manufacturing; Antibiotics; Biofilms; Bioremediation; biotechnology; Cellulose; Consortia; Customization; E coli; ecological differentiation; ecosystems; Efficiency; Ethanol; Fungi; Glucose; Hydrogels; Internal Medicine; living material; Materials science; Metabolism; Metabolites; Microbial activity; microbial communities; microbial consortia; Microorganisms; Niches; Process engineering; spatial niches; strains; Subpopulations; Synthetic biology; Yeast; microbial consortia; living material; spatial niches

The construction of synthetic microbial consortia has been considered a new frontier. However, maintaining artificial microbial communities remains challenging because the dominant strain eventually outcompetes the others. Inspired by natural ecosystems, one promising approach to assemble stable con...