Customized spatial niches for synthetic microbial consortia

The construction of synthetic microbial consortia has been considered a new frontier. However, maintaining artificial microbial communities remains challenging because the dominant strain eventually outcompetes the others. Inspired by natural ecosystems, one promising approach to assemble stable con...

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Bibliographic Details
Published inTrends in biotechnology (Regular ed.) Vol. 41; no. 12; pp. 1463 - 1466
Main Authors Gao, Hao, Jiang, Wankui, Zhang, Wenming, Jiang, Min, Xin, Fengxue
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.12.2023
Elsevier Limited
Subjects
Additive manufacturing
Antibiotics
Biofilms
Bioremediation
biotechnology
Cellulose
Consortia
Customization
E coli
ecological differentiation
ecosystems
Efficiency
Ethanol
Fungi
Glucose
Hydrogels
Internal Medicine
living material
Materials science
Metabolism
Metabolites
Microbial activity
microbial communities
microbial consortia
Microorganisms
Niches
Process engineering
spatial niches
strains
Subpopulations
Synthetic biology
Yeast
microbial consortia
living material
spatial niches
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Summary:The construction of synthetic microbial consortia has been considered a new frontier. However, maintaining artificial microbial communities remains challenging because the dominant strain eventually outcompetes the others. Inspired by natural ecosystems, one promising approach to assemble stable consortia is to construct spatial niches partitioning subpopulations and overlapping abiotic requirements.
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ISSN:0167-7799
1879-3096
1879-3096
DOI:10.1016/j.tibtech.2023.05.003