Role of Alpha/Beta Interferon in Venezuelan Equine Encephalitis Virus Pathogenesis: Effect of an Attenuating Mutation in the 5′ Untranslated Region

• Published in: Journal of Virology Vol. 75; no. 8; pp. 3706 - 3718
• Main Authors: White, L J, Wang, J G, Davis, N L, Johnston, R E
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.04.2001
• Subjects: 5' Untranslated Regions - genetics; Animals; Cell Line; Cricetinae; Encephalitis Virus, Venezuelan Equine - drug effects; Encephalitis Virus, Venezuelan Equine - genetics; Encephalitis Virus, Venezuelan Equine - pathogenicity; Encephalitis Virus, Venezuelan Equine - physiology; Encephalomyelitis, Venezuelan Equine - virology; Female; Gene Deletion; Interferon-alpha - metabolism; Interferon-alpha - pharmacology; Interferon-beta - metabolism; Interferon-beta - pharmacology; Membrane Proteins; Mice; Mice, Knockout; Mutation - genetics; Pathogenesis and Immunity; Phenotype; Receptor, Interferon alpha-beta; Receptors, Interferon - genetics; Receptors, Interferon - metabolism; Signal Transduction - drug effects; Survival Rate; Up-Regulation; Venezuelan equine encephalitis virus; Virulence - genetics; Virus Replication - drug effects
• ISSN: 0022-538X; 1098-5514
• DOI: 10.1128/JVI.75.8.3706-3718.2001

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