Acoustic Localization of Bragg Peak Proton Beams for Hadrontherapy Monitoring

Hadrontherapy makes it possible to deliver high doses of energy to cancerous tumors by using the large energy deposition in the Bragg-peak. However, uncertainties in the patient positioning and/or in the anatomical parameters can cause distortions in the calculation of the dose distribution. In orde...

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Published inSensors (Basel, Switzerland) Vol. 19; no. 9; p. 1971
Main Authors Otero, Jorge, Felis, Ivan, Ardid, Miguel, Herrero, Alicia
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 26.04.2019
MDPI
Subjects
Accuracy
Acoustic emission
acoustic localization
Acoustics
Bragg curve
Bragg peak
Computer simulation
Deposition
hadrontherapy
Iterative methods
Localization
Medical research
Monitoring
Monte Carlo simulation
Parameter uncertainty
piezoelectric ceramic
Proton beams
Radiation therapy
Sensors
thermoacoustic
Thermoacoustics
Tomography
Spain
piezoelectric ceramic
Bragg peak
hadrontherapy
thermoacoustic
acoustic localization
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Summary:Hadrontherapy makes it possible to deliver high doses of energy to cancerous tumors by using the large energy deposition in the Bragg-peak. However, uncertainties in the patient positioning and/or in the anatomical parameters can cause distortions in the calculation of the dose distribution. In order to maximize the effectiveness of heavy particle treatments, an accurate monitoring system of the deposited dose depending on the energy, beam time, and spot size is necessary. The localized deposition of this energy leads to the generation of a thermoacoustic pulse that can be detected using acoustic technologies. This article presents different experimental and simulation studies of the acoustic localization of thermoacoustic pulses captured with a set of sensors around the sample. In addition, numerical simulations have been done where thermo-acoustic pulses are emitted for the specific case of a proton beam of 100 MeV.
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This is an extension version of conference paper: Otero, J.; Ardid, M.; Herrero, A; Felis, I. Acoustic Location of Bragg Peak for Hadrontherapy Monitoring. In Proceedings of the 5th International Electronic Conference on Sensors and Applications, 15–30 November 2018.
ISSN:1424-8220
1424-8220
DOI:10.3390/s19091971