Patterns of recurrence following curative resection alone for adenocarcinoma of the rectum and sigmoid colon

Two‐hundred‐four patients with previously untreated adenocarcinoma of rectum, rectosigmoid, and sigmoid colon were retrospectively evaluated to determine patterns of recurrence following curative resection. Seventy‐eight (38%) subsequently developed recurrent disease. Of these, 40% (31/78) presented...

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Published inCancer Vol. 48; no. 6; pp. 1492 - 1495
Main Authors Rao, A. R., Kagan, A. R., Chan, P. M., Gilbert, H. A., Nussbaum, H., Hintz, B. L.
Format Journal Article
LanguageEnglish
Published New York Wiley Subscription Services, Inc., A Wiley Company 15.09.1981
Subjects
Adenocarcinoma - surgery
Adult
Aged
Female
Humans
Male
Middle Aged
Neoplasm Metastasis
Neoplasm Recurrence, Local - etiology
Neoplasm Staging
Prognosis
Rectal Neoplasms - surgery
Retrospective Studies
Sigmoid Neoplasms - surgery
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Summary:Two‐hundred‐four patients with previously untreated adenocarcinoma of rectum, rectosigmoid, and sigmoid colon were retrospectively evaluated to determine patterns of recurrence following curative resection. Seventy‐eight (38%) subsequently developed recurrent disease. Of these, 40% (31/78) presented with local recurrence alone, 28% (22/78) with regional recurrence, 15% (12/78) with concomitant local recurrence and distant metastasis, and 17% (13/78) with distant metastasis alone. The degree of tumor anaplasia and depth of tumor penetration into the bowel wall influenced the rate of local recurrence. Through five years local recurrence without clinical evidence of distant metastasis was the most common cause of death. Need for adjuvant radiation therapy is discussed.
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ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(19810915)48:6<1492::AID-CNCR2820480636>3.0.CO;2-K