Posterior reversible encephalopathy syndrome as a multiple sclerosis relapse mimic during interferon therapy

• Published in: Clinical neurology and neurosurgery Vol. 249; p. 108666
• Main Authors: Dias da Costa, Mariana, Leal Rato, Miguel, Ferreira, João, de Sá, João, Santos, Mónica
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.02.2025; Elsevier; Elsevier Limited
• Subjects: Blood pressure; Blood-brain barrier; Brain - pathology; Diagnosis, Differential; Edema; Editing; Encephalopathy; Humans; Hypertension; Interferon; Interferon-beta - adverse effects; Interferon-beta - therapeutic use; Intracranial stenosis; Magnetic Resonance Imaging; Male; Middle Aged; Multiple sclerosis; Multiple Sclerosis, Relapsing-Remitting - diagnosis; Multiple Sclerosis, Relapsing-Remitting - drug therapy; Neurology; Neurosurgery; Patients; Posterior Leukoencephalopathy Syndrome - chemically induced; Posterior Leukoencephalopathy Syndrome - diagnosis; Posterior Leukoencephalopathy Syndrome - pathology; PRES; Recurrence; Spinal cord; Steroids; Substantia alba; Supervision; Multiple sclerosis; Interferon; PRES; Intracranial stenosis

Posterior reversible encephalopathy syndrome is a rare syndrome involving the subcortical cerebral white matter. We describe the case of a 63-year-old male patient with relapsing remitting multiple sclerosis under interferon beta therapy and acute onset of atypical unilateral posterior reversible en...