Targeting ferroptosis: New perspectives of Chinese herbal medicine in the treatment of diabetes and its complications

Ferroptosis is a non-apoptotic mode of cell death. A large number of studies have confirmed that ferroptosis plays a vital role in the occurrence and development of diabetes and diabetic complications. Previous studies have found that Chinese herbal medicines have very promising results in the preve...

Full description

Saved in:
Bibliographic Details
Published inHeliyon Vol. 9; no. 12; p. e22250
Main Authors Liu, Cuiping, Wang, Wuxi, Gu, Junling
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.12.2023
Elsevier
Subjects
Chinese herbal medicine
Diabetes
Diabetic complications
Ferroptosis
Natural compounds
Review
Ferroptosis
Chinese herbal medicine
Diabetic complications
Diabetes
Natural compounds
Online AccessGet full text

Cover

More Information
Summary:Ferroptosis is a non-apoptotic mode of cell death. A large number of studies have confirmed that ferroptosis plays a vital role in the occurrence and development of diabetes and diabetic complications. Previous studies have found that Chinese herbal medicines have very promising results in the prevention and treatment of diabetes and diabetic complications, and some of these herbs or herbal natural compounds may act via the inhibition of ferroptosis. In this review, we summarized the relationship between ferroptosis and diabetes and diabetic complications, and discussed its molecular mechanisms. We also reviewed the published studies of herbal medicines or herbal natural compounds that improved diabetes or diabetic complications via the ferroptosis pathway. In addition, we are trying to provide new insights for better treatment of diabetes and diabetic complications with Chinese herbal medicine and its herbal compounds.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:2405-8440
2405-8440
DOI:10.1016/j.heliyon.2023.e22250