Ibuprofen for Ductus Arteriosus Months after Birth

Ibuprofen is a well-known agent used to treat patent ductus arteriosus in preterm neonates in the first days of life. In the current case report we illustrate the potential use of ibuprofen in two preterm neonates 60 and 88 days after birth, respectively. To our knowledge, this is the first report o...

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Bibliographic Details
Published inCase reports in pediatrics Vol. 2016; no. 2016; pp. 1 - 3
Main Authors Simons, S. H. P., Reiss, Irwin, van Beynum, Ingrid M., Frauenfelder, Odile
Format Journal Article
LanguageEnglish
Published Cairo, Egypt Hindawi Publishing Corporation 01.01.2016
Hindawi Limited
Wiley
Subjects
Case Report
Ductus arteriosus
Ibuprofen
Infants (Premature)
Patient outcomes
Physiological aspects
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Summary:Ibuprofen is a well-known agent used to treat patent ductus arteriosus in preterm neonates in the first days of life. In the current case report we illustrate the potential use of ibuprofen in two preterm neonates 60 and 88 days after birth, respectively. To our knowledge, this is the first report on the effects of ibuprofen on patent ductus arteriosus in preterm newborns after months of life. These cases suggest that the ductus arteriosus does not become refractory for ibuprofen after the first days of life. Late closure of the duct with ibuprofen might still improve the cardiorespiratory condition and prevent infants from surgical closure. Controlled trials are necessary to further study these findings.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Academic Editor: Jonathan Muraskas
ISSN:2090-6803
2090-6811
DOI:10.1155/2016/2659389