Cancer-associated keratinocytes: new members of the microenvironment in head and neck cancer

The tumor microenvironment is a complex ecosystem of malignant and nonmalignant cells and extracellular proteins that work together to enhance tumor progression. We identified a mechanism in which adjacent nonmalignant epithelium enhances invasion of squamous cell carcinoma, thereby expanding the tu...

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Bibliographic Details
Published inMolecular & cellular oncology Vol. 8; no. 4; p. 1933329
Main Authors Danella, Erika B., Costa De Medeiros, Marcell, D'Silva, Nisha J.
Format Journal Article
LanguageEnglish
Published United States Taylor & Francis 04.07.2021
Taylor & Francis Group
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Author’s Views
deleted in malignant brain tumors 1
Invasion
metastasis
tumor recurrence
tumor recurrence
metastasis
deleted in malignant brain tumors 1
Invasion
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Summary:The tumor microenvironment is a complex ecosystem of malignant and nonmalignant cells and extracellular proteins that work together to enhance tumor progression. We identified a mechanism in which adjacent nonmalignant epithelium enhances invasion of squamous cell carcinoma, thereby expanding the tumor microenvironment to include cancer-associated keratinocytes.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:2372-3556
2372-3556
DOI:10.1080/23723556.2021.1933329