Dopaminergic afferents to the mesencephalic trigeminal nucleus of the rat: a light and electron microscope immunocytochemistry study

The localization and sources of dopaminergic projections on the primary afferent neurons in the mesencephalic trigeminal nucleus (Me5) of the rat were studied using light and electron microscopic immunocytochemical staining techniques combined with anterograde and retrograde neuroanatomical tract tr...

Full description

Saved in:
Bibliographic Details
Published inBrain research Vol. 514; no. 2; p. 343
Main Authors Copray, J C, Liem, R S, Ter Horst, G J, van Willigen, J D
Format Journal Article
LanguageEnglish
Published Netherlands 30.04.1990
Subjects
Animals
Dopamine - metabolism
Dopamine - physiology
Hypothalamus, Middle - cytology
Hypothalamus, Middle - metabolism
Immunohistochemistry
Male
Rats
Rats, Inbred Strains
Substantia Nigra - cytology
Substantia Nigra - metabolism
Tegmentum Mesencephali - cytology
Tegmentum Mesencephali - metabolism
Trigeminal Nuclei - metabolism
Trigeminal Nuclei - ultrastructure
Online AccessGet more information

Cover

More Information
Summary:The localization and sources of dopaminergic projections on the primary afferent neurons in the mesencephalic trigeminal nucleus (Me5) of the rat were studied using light and electron microscopic immunocytochemical staining techniques combined with anterograde and retrograde neuroanatomical tract tracing methods. Me5 neurons were found to receive a dopaminergic input that is part of a dopaminergic fibre plexus extending over the neighbouring nucleus parabrachialis and locus coeruleus. These dopaminergic afferents originate from the substantia nigra, the ventral tegmental area and the medial hypothalamus.
ISSN:0006-8993
DOI:10.1016/0006-8993(90)91430-O