Animal- versus in vitro-derived antibodies: avoiding the extremes

Recent recommendations from the European Union Reference Laboratory regarding the generation of antibodies using animals have stimulated significant debate. Here, four of the scientists who served on the Scientific Advisory Committee provide clarification of their views regarding the use of animals...

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Bibliographic Details
Published inmAbs Vol. 13; no. 1; p. 1950265
Main Authors Bradbury, Andrew R.M., Dübel, Stefan, Knappik, Achim, Plückthun, Andreas
Format Journal Article
LanguageEnglish
Published United States Taylor & Francis 01.01.2021
Taylor & Francis Group
Subjects
Animal Use Alternatives
Antibodies
Antibody
antibody discovery
antibody therapeutics
European Union
Humans
immunization
phage display
antibody therapeutics
Antibody
phage display
immunization
antibody discovery
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Summary:Recent recommendations from the European Union Reference Laboratory regarding the generation of antibodies using animals have stimulated significant debate. Here, four of the scientists who served on the Scientific Advisory Committee provide clarification of their views regarding the use of animals and in vitro platforms in antibody generation. Abbreviations: EURL ECVAM, European Union Reference Laboratory for alternatives to animal testing. ESAC, EURL ECVAM Scientific Advisory Committee
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Undefined-1
ObjectType-Feature-3
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ISSN:1942-0862
1942-0870
DOI:10.1080/19420862.2021.1950265