Origin, dietary exposure, and toxicity of endocrine-disrupting food chemical contaminants: A comprehensive review

• Published in: Heliyon Vol. 9; no. 7; p. e18140
• Main Authors: Peivasteh-roudsari, Leila, Barzegar-bafrouei, Raziyeh, Sharifi, Kurush Aghbolagh, Azimisalim, Shamimeh, Karami, Marziyeh, Abedinzadeh, Solmaz, Asadinezhad, Shabnam, Tajdar-oranj, Behrouz, Mahdavi, Vahideh, Alizadeh, Adel Mirza, Sadighara, Parisa, Ferrante, Margherita, Conti, Gea Oliveri, Aliyeva, Aynura, Mousavi Khaneghah, Amin
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.07.2023; Elsevier
• Subjects: Dietary exposure; Endocrine disruption; Food safety; Public health; Endocrine disruption; Food safety; Public health; Dietary exposure
• ISSN: 2405-8440; 2405-8440
• DOI: 10.1016/j.heliyon.2023.e18140

Endocrine-disrupting chemicals (EDCs) are a growing public health concern worldwide. Consumption of foodstuffs is currently thought to be one of the principal exposure routes to EDCs. However, alternative ways of human exposure are through inhalation of chemicals and dermal contact. These compounds in food products such as canned food, bottled water, dairy products, fish, meat, egg, and vegetables are a ubiquitous concern to the general population. Therefore, understanding EDCs' properties, such as origin, exposure, toxicological impact, and legal aspects are vital to control their release to the environment and food. The present paper provides an overview of the EDCs and their possible disrupting impact on the endocrine system and other organs.