Microwave ablation for lung cancer patients with a single lung: Clinical evaluation of 11 cases

• Published in: Thoracic cancer Vol. 9; no. 5; pp. 548 - 554
• Main Authors: Yang, Xia, Ye, Xin, Zhang, Licheng, Geng, Dianzhong, Du, Zhenli, Yu, Guohua, Ren, Haipeng, Wang, Jiao, Huang, Guanghui, Wei, Zhigang, Ni, Yang, Li, Wenhong, Han, Xiaoying
• Format: Journal Article
• Language: English
• Published: Melbourne John Wiley & Sons Australia, Ltd 01.05.2018; John Wiley & Sons, Inc
• Subjects: Ablation (Surgery); Aged; Bronchitis; Cancer patients; Cancer therapies; Cardiovascular disease; Care and treatment; Catheter Ablation - adverse effects; Chemotherapy; CT imaging; Diabetes; Disease-Free Survival; Female; Health aspects; Heart; Hemoptysis - etiology; Hemoptysis - pathology; Hemorrhage - etiology; Hemorrhage - pathology; Hospitals; Humans; Lung - pathology; Lung - radiation effects; Lung - surgery; Lung cancer; Lung cancer, Non-small cell; Lung Neoplasms - diagnostic imaging; Lung Neoplasms - pathology; Lung Neoplasms - radiotherapy; Male; Medical imaging; Metastasis; Microwave ablation; Microwaves - adverse effects; Microwaves - therapeutic use; Middle Aged; Neoplasm Recurrence, Local - diagnostic imaging; Neoplasm Recurrence, Local - pathology; NSCLC; Original; Patients; Pleural Effusion - etiology; Pleural Effusion - pathology; Pneumonectomy; Pneumothorax - etiology; Pneumothorax - pathology; Radiation therapy; Retrospective Studies; single lung; Tomography, X-Ray Computed; Tumors; China; Microwave ablation; pneumonectomy; NSCLC; single lung
• ISSN: 1759-7706; 1759-7714
• DOI: 10.1111/1759-7714.12611

Background The study was conducted to retrospectively evaluate the safety and effectiveness of computed tomography (CT)‐guided percutaneous microwave ablation (MWA) for peripheral non‐small cell lung cancer (NSCLC) in 11 patients with a single lung after pneumonectomy. Methods From May 2011 to March 2015, 11 single‐lung patients (8 men and 3 women; mean age 60.3 years, range 46–71) with peripheral NSCLC underwent 12 sessions of MWA. Eleven tumors measuring 13–52 mm (mean 30.2 mm) were treated. Follow‐up was performed via CT scan at 1, 3, 6, 12, 18, and 24 months after the procedure and annually thereafter. Clinical outcomes were evaluated and complications after MWA were summarized. Results At a median follow‐up period of 20 months (range 6–38), four patients showed evidence of local recurrence at a rate of 36.4% (4/11). Median overall survival was 20 months. The overall survival rates at one, two, and three years after MWA were 88.7%, 63.6%, and 42.3%, respectively. Complications after MWA included pneumothorax (33.3%), hemoptysis (33.3%), intrapulmonary bleeding (25%), pleural effusion (16.7%), and pulmonary infection (8.3%). None of the patients died during the procedure or in the 30 days after MWA. Conclusion CT‐guided percutaneous MWA is safe and effective for the treatment of peripheral NSCLC in patients with a single lung after prior pneumonectomy.