Applications of array technology: identification of molecular targets in bladder cancer

High-throughput microarrays are being used in expression profiling analyses with the objectives of gene and pathway discovery, functional characterization of genes, and tumor subclassification. This review summarizes bladder cancer studies dealing with both in vitro models and clinical specimens, us...

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Bibliographic Details
Published inBritish journal of cancer Vol. 89; no. 12; pp. 2172 - 2177
Main Authors SANCHEZ-CARBAYO, M, CORDON-CARDO, C
Format Journal Article
LanguageEnglish
Published Basingstoke Nature Publishing Group 15.12.2003
Subjects
Biological and medical sciences
Bladder cancer
Cell Line, Tumor
Gene Expression Profiling - methods
Humans
Medical sciences
Minireview
Nephrology. Urinary tract diseases
Oligonucleotide Array Sequence Analysis - methods
Signal Transduction - genetics
Tumors
Tumors of the urinary system
Urinary Bladder Neoplasms - classification
Urinary Bladder Neoplasms - genetics
Urinary tract. Prostate gland
Urinary system disease
Cancerology
DNA microarrays
bladder cancer molecular target
Technology
DNA chip
tissue arrays
Bladder disease
Malignant tumor
Urinary tract disease
Bladder cancer
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Summary:High-throughput microarrays are being used in expression profiling analyses with the objectives of gene and pathway discovery, functional characterization of genes, and tumor subclassification. This review summarizes bladder cancer studies dealing with both in vitro models and clinical specimens, using distinct microarray platforms for target discovery.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0007-0920
1532-1827
DOI:10.1038/sj.bjc.6601406