Two new alkaloids from the rhizome of Polygonatum sibiricum

• Published in: Journal of asian natural products research Vol. 7; no. 2; pp. 127 - 130
• Main Authors: Sun, Long-Ru, Li, Xian, Wang, Su-Xian
• Format: Journal Article
• Language: English
• Published: ABINGDON Taylor & Francis GroupAbingdon, UK 01.04.2005; Taylor & Francis
• Subjects: Alkaloids; Alkaloids - chemistry; Alkaloids - isolation & purification; Biological and medical sciences; Chemistry; Chemistry, Applied; Chemistry, Medicinal; Chromatography, Thin Layer; Drugs, Chinese Herbal - chemistry; General pharmacology; Indolizines - chemistry; Indolizines - isolation & purification; Life Sciences & Biomedicine; Medical sciences; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pharmacognosy. Homeopathy. Health food; Pharmacology & Pharmacy; Pharmacology. Drug treatments; Physical Sciences; Plant Sciences; Polygonatine A; Polygonatine B; Polygonatum - chemistry; Polygonatum sibiricum Redoute; Rhizome - chemistry; Science & Technology; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Asia; China; polygonatine B; polygonatine A; Polygonatum sibiricum Redoute; alkaloids; Indolizine derivatives; Monocotyledones; Ether; Angular nitrogen heterocycle; Pharmacognosy; Ketone; Primary alcohol; Medicinal plant; Alkaloids; Alkaloid; Liliaceae; Folk medicine; Angiospermae; Plant origin; Rhizome; Bicyclic compound; Polygonatine A; Isolation; Polygonatine B; Spermatophyta; Polygonatum sibincunt Redoute; Structural analysis
• ISSN: 1028-6020; 1477-2213
• DOI: 10.1080/10286020310001625157

Two new alkaloids named polygonatine A (1) and polygonatine B (2) have been isolated from the rhizome of Polygonatum sibiricum Redoute (Liliaceae). By spectral data (IR, UV, MS, 1D and 2D NMR) and chemical evidence, their structures were elucidated as 3-hydroxymethyl-5,6,7,8-tetrahydroindolizin-8-one (1) and 3-ethoxymethyl-5,6,7,8-tetrahydroindolizin-8-one (2).