Brief Report: Clusters and Trajectories Across the Autism and/or ADHD Spectrum

Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD) frequently co-occur and show high genetic correlation. With the introduction of DSM-5, there is a new concept of an ASD and/or ADHD spectrum (ASD/ADHD). This study aimed to identify predictors of severity and need of...

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Bibliographic Details
Published inJournal of autism and developmental disorders Vol. 48; no. 10; pp. 3629 - 3636
Main Authors LaBianca, S., Pagsberg, A. K., Jakobsen, K. D., Demur, A. B., Bartalan, M., LaBianca, J., Werge, T.
Format Journal Article
LanguageEnglish
Published New York Springer US 01.10.2018
Springer
Springer Nature B.V
Subjects
Academic achievement
Attention Deficit Hyperactivity Disorder
Autism
Behavioral Science and Psychology
Brief Report
Care and treatment
Child and School Psychology
Clinics
Comorbidity
Correlation
Demography
Development and progression
Forecasts and trends
Foreign Countries
Genetic susceptibility
Genetics
Health care
Health Services
Hospitalization
Influence
Medical care utilization
Mental Health
Multivariate Analysis
Neurosciences
Patients
Pediatrics
Pervasive Developmental Disorders
Predictor Variables
Psychology
Public Health
Severity
Severity (of Disability)
Undiagnosed
Denmark
Clusters of life trajectories
ADHD
National Health Register
ASD
Genetic risk
Co-morbidity
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Summary:Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD) frequently co-occur and show high genetic correlation. With the introduction of DSM-5, there is a new concept of an ASD and/or ADHD spectrum (ASD/ADHD). This study aimed to identify predictors of severity and need of healthcare within this spectrum. 39 families with multiple individuals affected by ASD/ADHD were recruited from a psychiatric clinic. Diagnoses, functional and demographic characteristics were retrieved from journals while hospital admissions were identified in the Danish health register. An estimated fraction of 31% ASD/ADHD patients had never been hospitalized and 35% remained undiagnosed despite hospitalization. Cluster analysis identified trajectories that discriminate age of diagnosis, educational attainment to degree of severity, need of hospitalization and genetic risk.
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ISSN:0162-3257
1573-3432
DOI:10.1007/s10803-018-3618-6