Germinal Center Kinase Is Required for Optimal Jun N-Terminal Kinase Activation by Toll-Like Receptor Agonists and Is Regulated by the Ubiquitin Proteasome System and Agonist-Induced, TRAF6-Dependent Stabilization

• Published in: Molecular and Cellular Biology Vol. 24; no. 20; pp. 9165 - 9175
• Main Authors: Zhong, Jian, Kyriakis, John M.
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.10.2004; Taylor & Francis
• Subjects: Animals; CD40 Antigens - metabolism; Cell Growth and Development; Cell Line; Enzyme Activation; Humans; Interferon Inducers - metabolism; Interleukin-1 - metabolism; JNK Mitogen-Activated Protein Kinases - metabolism; Lipid A - metabolism; Lipopolysaccharides - metabolism; MAP Kinase Kinase Kinase 1 - metabolism; Membrane Glycoproteins - agonists; Membrane Glycoproteins - metabolism; Poly I-C - metabolism; Proteasome Endopeptidase Complex - metabolism; Proteasome Inhibitors; Protein-Serine-Threonine Kinases - genetics; Protein-Serine-Threonine Kinases - metabolism; Receptors, Cell Surface - agonists; Receptors, Cell Surface - metabolism; RNA Interference; Signal Transduction - physiology; TNF Receptor-Associated Factor 6 - metabolism; Toll-Like Receptors; Ubiquitin - metabolism
• ISSN: 0270-7306; 1098-5549; 1098-5549
• DOI: 10.1128/MCB.24.20.9165-9175.2004

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