Three‐dimensional navigation‐guided thoracoscopic combined subsegmentectomy for intersegmental pulmonary nodules

• Published in: Thoracic cancer Vol. 10; no. 1; pp. 41 - 46
• Main Authors: Wu, Wei‐Bing, Xia, Yang, Pan, Xiang‐Long, Wang, Jun, He, Zhi‐Cheng, Xu, Jing, Wen, Wei, Xu, Xin‐Feng, Zhu, Quan, Chen, Liang
• Format: Journal Article
• Language: English
• Published: Melbourne John Wiley & Sons Australia, Ltd 01.01.2019; John Wiley & Sons, Inc; Wiley
• Subjects: Adult; Aged; Aged, 80 and over; Angiography; Bronchography; Bronchography and angiography; Design; Female; Humans; Hyperplasia; Imaging, Three-Dimensional; Lung - diagnostic imaging; Lung - pathology; Lung - surgery; Lung cancer; Mastectomy, Segmental; Medical imaging; Middle Aged; Multiple Pulmonary Nodules - diagnostic imaging; Multiple Pulmonary Nodules - physiopathology; Multiple Pulmonary Nodules - surgery; Original; Pneumonectomy; pulmonary nodule; segmentectomy; Simulation; Thoracic Surgery, Video-Assisted - methods; thoracoscopy; Three dimensional imaging; three‐dimensional computed tomography; Tomography, X-Ray Computed; Veins & arteries; Germany; Bronchography and angiography; pulmonary nodule; segmentectomy; thoracoscopy; three-dimensional computed tomography
• ISSN: 1759-7706; 1759-7714
• DOI: 10.1111/1759-7714.12897

Background Extended or combined segmentectomies are usually adapted for intersegmental pulmonary nodules. This study explored precise combined subsegmentectomy (CSS) under the guidance of three‐dimensional computed tomography bronchography and angiography (3D‐CTBA). Methods The definition of a pulmonary intersegmental nodule was based on a minimum distance between the nodule and the involved intersegmental veins in the preoperative 3D‐CTBA being less than the size of the nodule. Centering on the involved intersegmental vein, two adjacent subsegments belonging to the different segments were combined as a resected unit. Results We retrospectively reviewed the records of 47 patients (mean age 53.6 ± 12.3, range: 26–81 years) who underwent CSS. Thirty‐nine (83.0%) nodules were involved in most intersegmental locations of the upper lobes; the remainder in the lower lobes. The mean nodule size was 0.86 ± 0.32 cm; the mean margin width was 2.20 ± 0.38 cm. Pathological stages included: Tis (8 cases), T1mi (16), IA1 (T1aN0M0, 13), and IA2 (T1bN0M0, 5). Pathological diagnoses included: invasive adenocarcinoma (18 cases), minimally invasive adenocarcinoma (16), adenocarcinoma in situ (8), atypical adenomatous hyperplasia (3), and benign (2). The average operative duration was 190.8 ± 54.9 minutes; operative hemorrhage was 42.7 ± 23.0 mL; 5.8 ± 2.8 lymph nodes dissected had not metastasized; the duration of postoperative chest tube drainage was 3.0 ± 1.8 days; and the postoperative hospital stay was 5.3 ± 2.4 days. Conclusions Under 3D navigation, thoracoscopic CSS is a safe technique for intersegmental nodules, sparing more pulmonary parenchyma and ensuring safe margins to achieve anatomical resection.