Long non‐coding RNAs and prostate cancer

• Published in: Cancer science Vol. 108; no. 11; pp. 2107 - 2114
• Main Authors: Misawa, Aya, Takayama, Ken‐ichi, Inoue, Satoshi
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.11.2017; John Wiley and Sons Inc
• Subjects: Androgen; androgen receptor; Androgen receptors; Biomarkers; Biomarkers, Tumor - genetics; Carcinogenesis; Castration; castration resistant prostate cancer; Cell growth; Gene Expression Regulation, Neoplastic; Humans; Kinases; long non‐coding RNA; Male; Medical Overuse; Nucleotides; Prostate cancer; Prostatic Neoplasms - diagnosis; Prostatic Neoplasms - genetics; Prostatic Neoplasms - pathology; Review; Ribonucleic acid; RNA; RNA, Long Noncoding - genetics; Therapeutic applications; Unsolicited Review; prostate cancer; long non-coding RNA; androgen receptor; Androgen; castration resistant prostate cancer

Long non‐coding RNAs (lncRNAs) are RNA transcripts larger than 200 nucleotides that do not code for proteins the aberrant expression of which has been documented in various types of cancer, including prostate cancer. Lack of appropriate sensitive and specific biomarkers for prostate cancer has led t...