Gene expression profiling in AML with normal karyotype can predict mutations for molecular markers and allows novel insights into perturbed biological pathways

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Bibliographic Details
Published inLeukemia Vol. 24; no. 6; pp. 1216 - 1220
Main Authors KOHLMANN, A, BULLINGER, L, HAFERLACH, T, THIEDE, C, SCHAICH, M, SCHNITTGER, S, DÖHNER, K, DUGAS, M, KLEIN, H.-U, DÖHNER, H, EHNINGER, G
Format Journal Article
LanguageEnglish
Published Avenel, NJ Nature Publishing Group 01.06.2010
Subjects
Biological and medical sciences
Biomarkers, Tumor - genetics
Biomarkers, Tumor - metabolism
Blotting, Western
CCAAT-Enhancer-Binding Proteins - genetics
fms-Like Tyrosine Kinase 3 - genetics
Gene expression
Gene Expression Profiling
Gene mutations
Genetic markers
Hematologic and hematopoietic diseases
Humans
Karyotypes
Karyotyping
Leukemia, Myeloid, Acute - classification
Leukemia, Myeloid, Acute - genetics
Leukemia, Myeloid, Acute - metabolism
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Medical sciences
Mutation
Mutation - genetics
Nuclear Proteins - genetics
Oligonucleotide Array Sequence Analysis
Predictive Value of Tests
Reverse Transcriptase Polymerase Chain Reaction
Risk Assessment
RNA, Messenger - genetics
RNA, Messenger - metabolism
Signal Transduction
Acute myelogenous leukemia
Hematology
Genetic marker
Cytogenetics
Genetics
Malignant hemopathy
Molecular marker
Mutation
Predictive factor
Karyotype
Cancer
Gene expression profile
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Bibliography:SourceType-Other Sources-1
content type line 63
ObjectType-Correspondence-1
ISSN:0887-6924
1476-5551
DOI:10.1038/leu.2010.73