Involvement of SMAp in the intention-related long latency stretch reflex modulation: A TMS study

• Published in: Neuroscience Vol. 246; pp. 329 - 341
• Main Authors: Spieser, L, Aubert, S, Bonnard, M
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Ltd 29.08.2013; Elsevier; Elsevier - International Brain Research Organization
• Subjects: Adult; Biological and medical sciences; Cognitive science; Female; Fundamental and applied biological sciences. Psychology; Humans; Intention; Male; Motor Cortex - physiology; Motor-Evoked Potentials; Neurology; Neuroscience; primary motor cortex; Reaction Time - physiology; Reflex, Stretch - physiology; stretch reflex; Supplementary Motor Area proper; TMS; Transcranial Magnetic Stimulation - methods; Vertebrates: nervous system and sense organs; M1; Motor-Evoked Potentials; dPMC; SMAp; ERPs; Transcranial Magnetic Stimulation; Long Latency Stretch Reflex; analysis of variance; FCR; ANOVA; ECR; Event-Related Potentials; Supplementary Motor Area proper; stretch reflex; flexor carpi radialis; TMS; LLSR; dorsal premotor cortex; extensor carpi radialis; primary motor cortex; MEPs; Stretch reflex; Supplementary motor area; Motor pathway; Motor cortex; Central nervous system; Electrophysiology; Motor evoked potential; Encephalon
• ISSN: 0306-4522; 1873-7544
• DOI: 10.1016/j.neuroscience.2013.05.005

Highlights • We compare effects of TMS over SMAp vs. M1 on intentional stretch reflex modulation. • As for M1, SMAp transient inactivation decreases the reflex modulation. • The effect of SMAp inactivation precedes the effect of M1 inactivation. • TMS over SMAp always elicits a Motor-Evoked Potential followed by a Silent Period. • SMAp MEPs amplitude is modulated according to the subject’s intention.