Mismatch of structural and functional tonotopy for natural sounds in the auditory midbrain

• Published in: Neuroscience Vol. 258; pp. 192 - 203
• Main Authors: Portfors, C.V, Roberts, P.D
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Ltd 31.01.2014; Elsevier
• Subjects: Acoustic Stimulation; Acoustics; Action Potentials; Animals; Auditory Perception - physiology; Biological and medical sciences; Cochlea - physiology; distortion products; Ear and associated structures. Auditory pathways and centers. Hearing. Vocal organ. Phonation. Sound production. Echolocation; Female; frequency tuning; Fundamental and applied biological sciences. Psychology; Hearing - physiology; Inferior Colliculi - physiology; inferior colliculus; Mice; Mice, Inbred CBA; Models, Neurological; mouse; Neurology; Neurons - physiology; Nonlinear Dynamics; spatial organization; Ultrasonics; Vertebrates: nervous system and sense organs; Vocalization, Animal; vocalizations; CF; spatial organization; MT; minimal threshold; mouse; PSTHs; characteristic frequency; NMSE; SI; normalized mean square error; distortion products; inferior colliculus; vocalizations; IC; post-stimulus time histograms; selectivity index value; frequency tuning; Rodentia; Central nervous system; Midbrain; Encephalon; Vertebrata; Mammalia; Colliculus inferior; Mouse; Animal; Auditory pathway; Tonotopy
• ISSN: 0306-4522; 1873-7544
• DOI: 10.1016/j.neuroscience.2013.11.012

Highlights • Neural responses to vocalizations are not well predicted by responses to tones. • Low-frequency neurons in the inferior colliculus encode high-frequency vocalizations. • High-frequency vocalizations create low-frequency distortion products. • Neurons in inferior colliculus use distortion products to encode vocalizations.