Prospects of genetic engineering of plants for phytoremediation of toxic metals

• Published in: Biotechnology advances Vol. 23; no. 2; pp. 97 - 114
• Main Authors: Eapen, Susan, D'Souza, S.F.
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Inc 01.03.2005; New York, NY Elsevier
• Subjects: Biodegradation, Environmental; Biological and medical sciences; Biotechnology; Chelator; Fundamental and applied biological sciences. Psychology; Gene Expression Regulation, Plant - physiology; Genetic engineering; Genetic Engineering - methods; Metals - isolation & purification; Metals - pharmacokinetics; Metals - toxicity; Phytoremediation; Plants, Genetically Modified - metabolism; Soil Pollutants - isolation & purification; Soil Pollutants - pharmacokinetics; Toxic metals; Water Pollutants, Chemical - isolation & purification; Water Pollutants, Chemical - pharmacokinetics; Water Purification - methods; Toxic metals; Genetic engineering; Phytoremediation; Metal
• ISSN: 0734-9750; 1873-1899
• DOI: 10.1016/j.biotechadv.2004.10.001

Bioremediation is gaining a lot of importance in recent times as an alternate technology for removal of elemental pollutants in soil and water, which require effective methods of decontamination. Phytoremediation—the use of green plants to remove, contain or render harmless environmental pollutants—may offer an effective, environmentally nondestructive and cheap remediation method. The use of genetic engineering to modify plants for metal uptake, transport and sequestration may open up new avenues for enhancing efficiency of phytoremediation. Metal chelator, metal transporter, metallothionein (MT), and phytochelatin (PC) genes have been transferred to plants for improved metal uptake and sequestration. Transgenic plants, which detoxify/accumulate cadmium, lead, mercury, arsenic and selenium have been developed. A better understanding of the mechanisms of rhizosphere interaction, uptake, transport and sequestration of metals in hyperaccumulator plants will lead to designing novel transgenic plants with improved remediation traits. As more genes related to metal metabolism are discovered, facilitated by the genome sequencing projects, new vistas will be opened up for development of efficient transgenic plants for phytoremediation.