A survey on the use of mice, pigs, dogs and monkeys as animal models in biomedical research in Spain

• Published in: Laboratory animal research Vol. 38; no. 1; p. 14
• Main Authors: Goñi-Balentziaga, Olatz, Ortega-Saez, Iván, Vila, Sergi, Azkona, Garikoitz
• Format: Journal Article
• Language: English
• Published: England BioMed Central 02.06.2022; BMC; 한국실험동물학회
• Subjects: Animal models; Animal welfare; Biomedical research; Laboratory animal; Laboratory animals; Legislation; Medical research; Monkeys & apes; Moral status; Pharmaceutical industry; Phylogenetic scale; Phylogeny; Research centers; Transgender persons; 수의학; Spain; Moral status; Phylogenetic scale; Biomedical research; Laboratory animal
• ISSN: 1738-6055; 2233-7660; 2233-7660
• DOI: 10.1186/s42826-022-00124-5

The use of animals in biomedical science remains controversial. An individual's level of concern is generally influenced by their culture, previous or current experience with animals, and the specific animal species in question. In this study we aimed to explore what people in Spain who had never or who no longer worked with laboratory animals thought of the use of mice, pigs, dogs and monkeys for biomedical research purposes. We also aimed to determine whether or not people currently involved in biomedical research with the aforementioned species felt their work was justified. The study comprised a total of 807 participants (never worked = 285, used to work = 56, currently working = 466), almost two thirds of whom were women. Our results revealed that the phylogenetic scale is an important factor in people's opinions of the use of certain species in research. The percentage of people who were against the use of dogs or monkeys was higher than that of those who were against the use of mice or pigs. The main reasons given for having stopped working with laboratory animals were change of professional career and change in research project. Participants who were currently working with animals believed that their work was justified, but said they did not talk about it with people outside their immediate social circle. Our findings suggest that there is a difference in moral status between monkeys and mice, as well as between companion animals (dogs) and farm animals (pigs). Our results support the idea that working with laboratory animals is a sensitive issue in Spain.