Prevalence, Deaths and Disability-Adjusted-Life-Years (DALYs) Due to Type 2 Diabetes and Its Attributable Risk Factors in 204 Countries and Territories, 1990-2019: Results From the Global Burden of Disease Study 2019

• Published in: Frontiers in endocrinology (Lausanne) Vol. 13; p. 838027
• Main Authors: Safiri, Saeid, Karamzad, Nahid, Kaufman, Jay S., Bell, Arielle Wilder, Nejadghaderi, Seyed Aria, Sullman, Mark J. M., Moradi-Lakeh, Maziar, Collins, Gary, Kolahi, Ali-Asghar
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 25.02.2022
• Subjects: burden; Diabetes Mellitus, Type 2 - epidemiology; Endocrinology; Global Burden of Disease; global epidemiology; Humans; Male; mortality; Prevalence; Quality-Adjusted Life Years; Risk Factors; type 2 diabetes mellitus; worldwide epidemiology; mortality; type 2 diabetes mellitus; prevalence; worldwide epidemiology; global epidemiology; burden
• ISSN: 1664-2392; 1664-2392
• DOI: 10.3389/fendo.2022.838027

To report the point prevalence, deaths and disability-adjusted-life-years (DALYs) due to type 2 diabetes and its attributable risk factors in 204 countries and territories during the period 1990-2019. We used the data of the Global Burden of Disease (GBD) Study 2019 to report number and age-standardised rates per 100 000 population of type 2 diabetes. Estimates were reported with 95% uncertainty intervals (UIs). In 2019, the global age-standardised point prevalence and death rates for type 2 diabetes were 5282.9 and 18.5 per 100 000, an increase of 49% and 10.8%, respectively, since 1990. Moreover, the global age-standardised DALY rate in 2019 was 801.5 per 100 000, an increase of 27.6% since 1990. In 2019, the global point prevalence of type 2 diabetes was slightly higher in males and increased with age up to the 75-79 age group, decreasing across the remaining age groups. American Samoa [19876.8] had the highest age-standardised point prevalence rates of type 2 diabetes in 2019. Generally, the burden of type 2 diabetes decreased with increasing SDI (Socio-demographic Index). Globally, high body mass index [51.9%], ambient particulate matter pollution [13.6%] and smoking [9.9%] had the three highest proportions of attributable DALYs. Low and middle-income countries have the highest burden and greater investment in type 2 diabetes prevention is needed. In addition, accurate data on type 2 diabetes needs to be collected by the health systems of all countries to allow better monitoring and evaluation of population-level interventions.