Biosynthesis and regulation of carotenoids in Dunaliella: Progresses and prospects
Natural carotenoids are high in demand in global market owing to their widespread applications in nutrition, medicine, food coloring agent and cosmetic, as well as to the natural and healthy preference of consumers today. Some strains of Dunaliella are well known for their talent of massive β-carote...
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Published in | Biotechnology advances Vol. 26; no. 4; pp. 352 - 360 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Oxford
Elsevier Inc
01.07.2008
New York, NY Elsevier |
Subjects | |
Online Access | Get full text |
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Summary: | Natural carotenoids are high in demand in global market owing to their widespread applications in nutrition, medicine, food coloring agent and cosmetic, as well as to the natural and healthy preference of consumers today. Some strains of
Dunaliella are well known for their talent of massive β-carotene accumulation. Content of the high bioavailability stereoisomer of β-carotene, the 9-
cis stereoisomer, is highest in
Dunaliella among all the natural carotenoids sources. These valuable algae have been exploited commercially for β-carotene-rich
Dunaliella powder and natural β-carotene in many countries since 1980s. However, drawbacks of traditional production methods have hampered the worldwide promotion of carotenoids production with
Dunaliella. To shake off the dilemma, complete understanding of carotenogenic mechanism is urgent. Carotenogenic mechanism in
Dunaliella is described in present paper, including carotenogenic pathway and its regulation. Generally, it seems that carotenogenic pathway in
Dunaliella is close to the one of higher plants. It is known that reactive oxygen species (ROS) were involved in signal transduction for gene activation. Induction of ROS is in parallel with the enhanced β-carotene accumulation in
Dunaliella. It is suggested that ROS trigger massive carotenoids accumulation in
Dunaliella. It also revealed that relation may exist between enhanced β-carotene accumulation and lipid metabolism. For the talent of β-carotene synthesis, it is possible that
Dunaliella massively accumulates β-carotene and other high-value carotenoids by genetic technologies. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-3 ObjectType-Review-1 ObjectType-Feature-1 |
ISSN: | 0734-9750 1873-1899 |
DOI: | 10.1016/j.biotechadv.2008.03.004 |