Chronic Thromboembolic Pulmonary Hypertension (CTEPH): A Review of Another Sequel of Severe Post-Covid-19 Pneumonia

• Published in: Current problems in cardiology Vol. 48; no. 8; p. 101187
• Main Authors: Cueto-Robledo, Guillermo, Roldan-Valadez, Ernesto, Graniel-Palafox, Luis-Eugenio, Garcia-Cesar, Marisol, Torres-Rojas, Maria-Berenice, Enriquez-Garcia, Rocio, Cueto-Romero, Hector-Daniel, Rivera-Sotelo, Nathaly, Perez-Calatayud, Angel-Augusto
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.08.2023; Mosby-Year Book
• ISSN: 0146-2806; 1535-6280; 1535-6280
• DOI: 10.1016/j.cpcardiol.2022.101187

The spectrum of pulmonary parenchymal and vascular pathologies related to the COVID-19 have emerged. There is evidence of a specific susceptibility related to thrombotic microangiopathy in situ and a complex immune-inflammatory cascade, especially in the pulmonary vascular bed. The potential to lead to transient or self-correcting sequelae of pulmonary vascular injury will only become apparent with longer-term follow-up. In this review, we aimed to present the findings in a group of patients with severe pneumonia due to covid-19 complicated by acute pe documented by chest angiography, who during a follow-up of more than 3 months with oral anticoagulant met clinical, hemodynamic, and imaging criteria of chronic thromboembolic pulmonary hypertension. We present a brief review of the epidemiology, pathophysiology, clinical findings, comorbidities, treatment, and imaging findings of chronic thromboembolic pulmonary hypertension as a sequel of severe post-covid-19 pneumonia; and compared and discussed these findings with similar reports from the medical literature.