Basolateral amygdala activity during the retrieval of associative learning under anesthesia

• Published in: Neuroscience Vol. 233; pp. 146 - 156
• Main Authors: Fenton, G.E, Spicer, C.H, Halliday, D.M, Mason, R, Stevenson, C.W
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Ltd 13.03.2013; Elsevier
• Subjects: Acoustic Stimulation; Amygdala - drug effects; Amygdala - physiology; Anatomical correlates of behavior; Anesthesia, General - veterinary; Anesthetics, Inhalation - pharmacology; Animals; Association Learning - drug effects; Association Learning - physiology; Awareness - drug effects; Awareness - physiology; basolateral amygdala; Behavioral psychophysiology; Biological and medical sciences; Conditioning, Classical - drug effects; Conditioning, Classical - physiology; consolidation; discrimination learning; Discrimination Learning - drug effects; Discrimination Learning - physiology; Electric Stimulation; Evoked Potentials - physiology; Fear - physiology; fear conditioning; Fundamental and applied biological sciences. Psychology; Isoflurane - pharmacology; Male; memory; Mental Recall - drug effects; Mental Recall - physiology; Neurology; Neuronal Plasticity; Olfactory Perception - physiology; Prefrontal Cortex - drug effects; Prefrontal Cortex - physiology; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Rats; Recognition (Psychology) - drug effects; Recognition (Psychology) - physiology; sensitization; medial prefrontal cortex; memory; fear conditioning; discrimination learning; early after learning; Post-L; consolidation; lateral amygdala; Post-E; Stim-A; CS; local field potential; mPFC; conditioned stimulus; electrical stimulation alone; analysis of variance; late after learning; ANOVA; LA; BLA; LFP; basolateral amygdala; sensitization; Amygdala; Rat; Memory; Rodentia; Central nervous system; Basal ganglion; Encephalon; Learning; Fear; Vertebrata; Mammalia; Acquisition process; Discrimination; Animal; Anesthesia; Conditioning
• ISSN: 0306-4522; 1873-7544
• DOI: 10.1016/j.neuroscience.2012.12.039

Highlights ► We examined BLA activity before and after discrimination learning under anesthesia. ► BLA activity was increased 1 h after CS+/electrical stimulation pairings. ► BLA activity was also increased 1 h after electrical stimulation alone. ► After learning, BLA activity increased during CS+, but not CS−, presentation. ► Discrimination learning under anesthesia can occur at the neural level in BLA.