Antiviral activity of quercetin-3-β-O-D-glucoside against Zika virus infection

Dear Editor, The 2015-2016 outbreak of Zika virus （ZIKV） fever, first reported in Brazil during early 2015 （Zanluca et al., 2015）, has infected millions of people and is a global public health concern. ZIKV infections are associated with fetal microcephaly, as well as neurological complications in h...

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Published inVirologica Sinica Vol. 32; no. 6; pp. 545 - 547
Main Authors Wong, Gary, He, Shihua, Siragam, Vinayakumar, Bi, Yuhai, Mbikay, Majambu, Chretien, Michel, Qiu, Xiangguo
Format Journal Article
LanguageEnglish
Published Singapore Springer Singapore 01.12.2017
KeAi Publishing Communications Ltd
Subjects
Animals
Antiviral activity
Antiviral Agents - administration & dosage
Antiviral Agents - pharmacology
antiviral properties
Biochemistry
Biomedical and Life Sciences
Biomedicine
brain
Brain stem
Cell culture
Cell lines
Cercopithecus aethiops
Disease Models, Animal
Fetuses
humans
Letter
Medical Microbiology
Mice, Knockout
Microbial Genetics and Genomics
Microbiology
Neural stem cells
Oncology
Quercetin
Quercetin - administration & dosage
Quercetin - analogs & derivatives
Quercetin - pharmacology
Survival Analysis
therapeutics
Tissue culture
Vero Cells
Viral Load
Viremia
Virology
Virus Replication - drug effects
Zika virus
Zika Virus - drug effects
Zika Virus - physiology
Zika Virus Infection - drug therapy
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Summary:Dear Editor, The 2015-2016 outbreak of Zika virus （ZIKV） fever, first reported in Brazil during early 2015 （Zanluca et al., 2015）, has infected millions of people and is a global public health concern. ZIKV infections are associated with fetal microcephaly, as well as neurological complications in humans. The virus can be shed in the semen and vaginal secretions of humans, leading to sexual transmission, and unexpectedly ZIKV infections cause severe damage to the male reproductive organs in male mice （Govero et al., 2016; Ma et al., 2016）.
Bibliography:42-1760/Q
Antiviral activity; quercetin-3-β-O-D-glucoside against Zika virus infection
Dear Editor, The 2015-2016 outbreak of Zika virus （ZIKV） fever, first reported in Brazil during early 2015 （Zanluca et al., 2015）, has infected millions of people and is a global public health concern. ZIKV infections are associated with fetal microcephaly, as well as neurological complications in humans. The virus can be shed in the semen and vaginal secretions of humans, leading to sexual transmission, and unexpectedly ZIKV infections cause severe damage to the male reproductive organs in male mice （Govero et al., 2016; Ma et al., 2016）.
SourceType-Scholarly Journals-1
ObjectType-Correspondence-1
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ObjectType-Article-1
ObjectType-Feature-2
ISSN:1674-0769
1995-820X
1995-820X
DOI:10.1007/s12250-017-4057-9