Low-dose CT for lung cancer screening

[...]the pending results of the NELSON trial, and the implications of them for EU screening policy, are not considered.[...]if the NELSON investigators believe screening is appropriate, and the findings of their own study won't change their conclusions, they should have clarified why they maint...

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Published inThe lancet oncology Vol. 19; no. 3; pp. e133 - e134
Main Authors Bach, Peter B, Brawley, Otis W, Silvestri, Gerard A
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.03.2018
Elsevier Limited
Subjects
Cancer screening
Cigarette smoking
Clinical medicine
Drug addiction
Early Detection of Cancer
Endorsements
Feasibility studies
Hematology, Oncology, and Palliative Medicine
Human subjects
Humans
Lung cancer
Lung Neoplasms
Medical research
Medical screening
Mortality
Prediction models
Radiation Dosage
Smoking cessation
Systematic review
Tomography
Tomography, X-Ray Computed
Europe
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ISSN1470-2045
1474-5488
1474-5488
DOI10.1016/S1470-2045(18)30117-7

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Summary:[...]the pending results of the NELSON trial, and the implications of them for EU screening policy, are not considered.[...]if the NELSON investigators believe screening is appropriate, and the findings of their own study won't change their conclusions, they should have clarified why they maintain human subjects in no screening follow-up of the study (in both groups to date).11 H Ashraf, Z Saghir, A Dirksen, Smoking habits in the randomised Danish Lung Cancer Screening Trial with low-dose CT: final results after a 5-year screening programme, Thorax, Vol. 69, 2014, 574-579 12 CM van der Aalst, KA van den Bergh, MC Willemsen, HJ de Koning, RJ van Klaveren, Lung cancer screening and smoking abstinence: 2 year follow-up data from the Dutch-Belgian randomised controlled lung cancer screening trial, Thorax, Vol. 65, 2010, 600-605 13 K ten Haaf, J Jeon, MC Tammemägi, Risk prediction models for selection of lung cancer screening candidates: a retrospective validation study, PLoS Med, Vol. 14, 2017, e1002277 14 World Medical Association, World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects, JAMA, Vol. 310, 2013, 2191-2194
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ISSN:1470-2045
1474-5488
1474-5488
DOI:10.1016/S1470-2045(18)30117-7