Carbapenem and Colistin Resistance in Enterobacter: Determinants and Clones
Enterobacter is a globally important pathogen. Here we clarify its taxonomy and review recent developments in its resistance to carbapenem and colistin, illustrating that Enterobacter has a large arsenal of mechanisms to grow under antimicrobial pressure. Further studies are required to decipher col...
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| Published in | Trends in microbiology (Regular ed.) Vol. 29; no. 6; pp. 473 - 476 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
England
Elsevier Ltd
01.06.2021
Elsevier Science Ltd |
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| Online Access | Get full text |
| ISSN | 0966-842X 1878-4380 1878-4380 |
| DOI | 10.1016/j.tim.2020.12.009 |
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| Abstract | Enterobacter is a globally important pathogen. Here we clarify its taxonomy and review recent developments in its resistance to carbapenem and colistin, illustrating that Enterobacter has a large arsenal of mechanisms to grow under antimicrobial pressure. Further studies are required to decipher colistin heteroresistance and understand why certain Enterobacter lineages have emerged clinically. |
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| AbstractList | Enterobacter is a globally important pathogen. Here we clarify its taxonomy and review recent developments in its resistance to carbapenem and colistin, illustrating that Enterobacter has a large arsenal of mechanisms to grow under antimicrobial pressure. Further studies are required to decipher colistin heteroresistance and understand why certain Enterobacter lineages have emerged clinically. Enterobacter is a globally important pathogen. Here we clarify its taxonomy and review recent developments in its resistance to carbapenem and colistin, illustrating that Enterobacter has a large arsenal of mechanisms to grow under antimicrobial pressure. Further studies are required to decipher colistin heteroresistance and understand why certain Enterobacter lineages have emerged clinically.Enterobacter is a globally important pathogen. Here we clarify its taxonomy and review recent developments in its resistance to carbapenem and colistin, illustrating that Enterobacter has a large arsenal of mechanisms to grow under antimicrobial pressure. Further studies are required to decipher colistin heteroresistance and understand why certain Enterobacter lineages have emerged clinically. |
| Author | Feng, Yu McNally, Alan Zong, Zhiyong |
| Author_xml | – sequence: 1 givenname: Zhiyong orcidid: 0000-0002-7675-260X surname: Zong fullname: Zong, Zhiyong email: zongzhiy@scu.edu.cn organization: Center of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, China – sequence: 2 givenname: Yu surname: Feng fullname: Feng, Yu organization: Center of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, China – sequence: 3 givenname: Alan surname: McNally fullname: McNally, Alan organization: Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/33431326$$D View this record in MEDLINE/PubMed |
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| Keywords | colistin resistance Enterobacter taxonomy carbapenem resistance antimicrobial resistance high-risk lineages |
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| SubjectTerms | Anti-Bacterial Agents - pharmacology Antibiotics Antiinfectives and antibacterials antimicrobial resistance Bacterial Proteins - genetics carbapenem resistance carbapenems Carbapenems - pharmacology Colistin Colistin - pharmacology colistin resistance Drug Resistance, Multiple, Bacterial Enterobacter Enterobacter - classification Enterobacter - drug effects Enterobacter - genetics high-risk lineages Humans Microbial Sensitivity Tests microbiology pathogens Taxonomy |
| Title | Carbapenem and Colistin Resistance in Enterobacter: Determinants and Clones |
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