Cardiac Regeneration and Stem Cells

• Published in: Physiological reviews Vol. 95; no. 4; pp. 1189 - 1204
• Main Authors: Zhang, Yiqiang, Mignone, John, MacLellan, W. Robb
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.10.2015
• Subjects: Animals; Cell Differentiation - physiology; Cellular biology; Heart; Heart - physiology; Heart Diseases - physiopathology; Humans; Maturation; Myocytes, Cardiac - physiology; Physiology; Regeneration - physiology; Reviews; Stem cells; Stem Cells - physiology; Tissue engineering

After decades of believing the heart loses the ability to regenerate soon after birth, numerous studies are now reporting that the adult heart may indeed be capable of regeneration, although the magnitude of new cardiac myocyte formation varies greatly. While this debate has energized the field of c...