Naturally acquired rabies virus infections in wild-caught bats

The study of a zoonotic disease requires an understanding of the disease incidence in animal reservoirs. Rabies incidence in bats submitted to diagnostic laboratories does not accurately reflect the true incidence in wild bat populations as a bias exists for testing bats that have been in contact wi...

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Bibliographic Details
Published inVector borne and zoonotic diseases (Larchmont, N.Y.) Vol. 12; no. 1; p. 55
Main Authors Davis, April, Gordy, Paul, Rudd, Robert, Jarvis, Jodie A, Bowen, Richard A
Format Journal Article
LanguageEnglish
Published United States 01.01.2012
Subjects
Animals
Antigens, Viral - isolation & purification
Brain - virology
Chiroptera
Rabies - epidemiology
Rabies - veterinary
Rabies - virology
Rabies virus - isolation & purification
Salivary Glands - virology
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Summary:The study of a zoonotic disease requires an understanding of the disease incidence in animal reservoirs. Rabies incidence in bats submitted to diagnostic laboratories does not accurately reflect the true incidence in wild bat populations as a bias exists for testing bats that have been in contact with humans or pets. This article details the rabies incidence in two species of bats collected from natural settings without such bias. In this study, brain smears from 0.6% and 2.5% of wild-caught and apparently healthy Tadarida brasiliensis and Eptesicus fuscus, respectively, were positive for rabies virus (RV) antigen. Conversely, 92% of the grounded T. brasiliensis were positive for RV. Serology performed on captive colony and sick bats reveal an immune response to rabies. This work illustrates the complex interplay between immunity, disease state, and the conundrum of RV maintenance in bats.
ISSN:1557-7759
DOI:10.1089/vbz.2011.0674