The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters

Abstract Natural products originating from microorganisms are frequently used in antimicrobial and anticancer drugs, pesticides, herbicides or fungicides. In the last years, the increasing availability of microbial genome data has made it possible to access the wealth of biosynthetic clusters respon...

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Bibliographic Details
Published inNucleic acids research Vol. 47; no. D1; pp. D625 - D630
Main Authors Blin, Kai, Pascal Andreu, Victòria, de los Santos, Emmanuel L C, Del Carratore, Francesco, Lee, Sang Yup, Medema, Marnix H, Weber, Tilmann
Format Journal Article
LanguageEnglish
Published England Oxford University Press 08.01.2019
Subjects
Bioinformatica
Bioinformatics
Database Issue
Databases, Genetic
Genome, Bacterial
Molecular Sequence Annotation
Multigene Family
Secondary Metabolism - genetics
Software
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Summary:Abstract Natural products originating from microorganisms are frequently used in antimicrobial and anticancer drugs, pesticides, herbicides or fungicides. In the last years, the increasing availability of microbial genome data has made it possible to access the wealth of biosynthetic clusters responsible for the production of these compounds by genome mining. antiSMASH is one of the most popular tools in this field. The antiSMASH database provides pre-computed antiSMASH results for many publicly available microbial genomes and allows for advanced cross-genome searches. The current version 2 of the antiSMASH database contains annotations for 6200 full bacterial genomes and 18,576 bacterial draft genomes and is available at https://antismash-db.secondarymetabolites.org/.
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ISSN:0305-1048
1362-4962
1362-4962
DOI:10.1093/nar/gky1060