Electrochemical detection of viruses and antibodies: A mini review

• Published in: Electrochemistry communications Vol. 116; p. 106762
• Main Authors: de Eguilaz, Miren Ruiz, Cumba, Loanda R., Forster, Robert J.
• Format: Journal Article
• Language: English
• Published: United States Elsevier B.V 01.07.2020; The Author(s). Published by Elsevier B.V; Elsevier
• Subjects: Biomarker detection; Biosensor; Electrochemical sensor; Immunosensor; Point of care device; Virus detection; Biomarker detection; Virus detection; Point of care device; Electrochemical sensor; Biosensor; Immunosensor
• ISSN: 1388-2481; 1873-1902; 1388-2481
• DOI: 10.1016/j.elecom.2020.106762

[Display omitted] •Highly sensitive electrochemical sensors for viral DNA enables early detection of disease.•Antibody testing allows the extent of disease and the immunity status of recovered individuals to be assessed.•Sample-to-answer devices open up testing in the community.•Integration of sensors, and wireless technologies enables autonomous, point-of-care applications.•Challenges remain in terms of selectivity, shelf-life, manufacturability and the use of sustainable materials. Near patient detection of viral infection represents a powerful approach for the control of emerging threats to global health. Moreover, the ability to identify individuals who have contracted the disease and developed antibodies that confer immunity is central to a return to normal daily activities. This review presents some of the recent advances in electrochemical sensors for the detection of viruses and their associated antibody profiles. Given the speed, portability, sensitivity and selectivity achieved using electrochemical detection, these sensor systems hold the promise of transformative change in clinical practice.