Comparison of gradient- and spin-echo imaging: CBF, CBV, and MTT measurements by bolus tracking

• Published in: Journal of magnetic resonance imaging Vol. 12; no. 3; pp. 411 - 416
• Main Authors: Simonsen, Claus Z., Østergaard, Leif, Smith, Donald F., Vestergaard-Poulsen, Peter, Gyldensted, Carsten
• Format: Journal Article
• Language: English
• Published: New York John Wiley & Sons, Inc 01.09.2000
• Subjects: Animals; Blood Flow Velocity - physiology; Blood Volume Determination; Brain - anatomy & histology; Brain - blood supply; CBF; Cerebrovascular Circulation; Contrast Media; Disease Models, Animal; dynamic susceptibility contrast imaging; Female; Gadolinium DTPA - administration & dosage; gradient echo; Hypercapnia - physiopathology; Hypocapnia - physiopathology; Image Enhancement - methods; Injections, Intravenous; Magnetic Resonance Imaging - methods; Models, Biological; MRI; Perfusion; Sensitivity and Specificity; spin echo; Swine

The authors measured cerebral blood flow (CBF), cerebral blood volume (CBV), and mean transit time (MTT) in pigs by gadodiamide bolus injections and the bolus tracking technique. Two different pulse sequences were applied and compared: gradient‐echo (GE) and spin‐echo (SE) echoplanar imaging (EPI)....