Use of the Sequential Organ Failure Assessment score for evaluating outcome among obstetric patients admitted to the intensive care unit

• Published in: International journal of gynecology and obstetrics Vol. 132; no. 3; pp. 332 - 336
• Main Authors: Jain, Shruti, Guleria, Kiran, Suneja, Amita, Vaid, Neelam B, Ahuja, Sharmila
• Format: Journal Article
• Language: English
• Published: United States Elsevier B.V 01.03.2016
• Subjects: Adult; Area Under Curve; Critical illness; Critical Illness - mortality; Critical Illness - therapy; Female; Hospitalization; Humans; India; Intensive care unit; Intensive Care Units; Morbidity; Near Miss, Healthcare - statistics & numerical data; Near-miss cases; Obstetric cases; Obstetrics and Gynecology; Organ Dysfunction Scores; Outcome Assessment (Health Care); Pregnancy; Pregnancy Complications - diagnosis; Prenatal Care; Prognostic score; Prospective Studies; ROC Curve; Sensitivity and Specificity; Sequential Organ Failure Assessment score; Severe maternal morbidity; Social Class; Treatment Outcome; Critical illness; Near-miss cases; Sequential Organ Failure Assessment score; Prognostic score; Severe maternal morbidity; Intensive care unit; Obstetric cases
• ISSN: 0020-7292; 1879-3479
• DOI: 10.1016/j.ijgo.2015.08.005

Abstract Objective To evaluate the prognostic value of the Sequential Organ Failure Assessment (SOFA) score among obstetric patients admitted to the intensive care unit (ICU). Methods A prospective study was conducted among 90 consecutive obstetric patients who were admitted to the ICU of Guru Teg Bahadur Hospital, Delhi, India, between October 6, 2010, and December 25, 2011. Maximum SOFA score was calculated for each of the six organ systems. Receiver operating characteristic curves were used to determine critical cutoff values for total, maximum total, and mean total SOFA scores at various time points. Results Total SOFA score at admission displayed an area under the curve (AUC) of 0.949, a cutoff value of at least 8.5, sensitivity of 86.7%, and specificity of 90.0%. Maximum total SOFA score had an AUC of 0.980, a cutoff value of at least 10.0, sensitivity of 96.7%, and specificity of 90.0%. Mean total SOFA score had an AUC of 0.997, a cutoff value of at least 9.0, sensitivity of 96.7%, and specificity of 96.7%. Conclusion In terms of discriminatory power for predicting mortality among obstetric patients admitted to the ICU, total SOFA score at admission was the most relevant, simple, and accurate measure.