Does Off-Pump Coronary Artery Bypass Grafting Negatively Impact Long-Term Survival and Freedom from Reintervention?

• Published in: BioMed research international Vol. 2013; no. 2013; pp. 1 - 8
• Main Authors: Daley, Siobhan, Chudasama, Dimple, Popescu, Florentina L., Husain, Mubassher, Raja, Shahzad G., Amrani, Mohamed
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 01.01.2013; John Wiley & Sons, Inc; Hindawi Limited
• Subjects: Aged; Allografts; Analysis; Cardiology; Cardiovascular Diseases - mortality; Cardiovascular Diseases - pathology; Cardiovascular Diseases - surgery; Clinical Study; Coronary artery bypass; Coronary Artery Bypass - methods; Coronary Artery Bypass - mortality; Coronary Artery Bypass, Off-Pump - methods; Coronary Artery Bypass, Off-Pump - mortality; Coronary vessels; Female; Health aspects; Heart attacks; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Mortality; Risk; Survivors; Treatment Outcome; United Kingdom; Veins & arteries; United Kingdom
• ISSN: 2314-6133; 2314-6141
• DOI: 10.1155/2013/602871

Recently published evidence has raised concerns about worse late mortality and increasing need for reintervention after off-pump coronary artery bypass grafting. We undertook this study to assess the impact of off-pump coronary artery bypass grafting on survival and freedom from reintervention at 10 years. From January 2002 to December 2002, 307 consecutive patients who had isolated multivessel off-pump coronary artery bypass grafting at our institution were compared to a control group of 397 patients that underwent multivessel on-pump coronary artery bypass grafting during the same period. In addition, univariate and risk-adjusted comparisons between the two groups were performed at 10 years. Kaplan-Meier survival was similar for the two cohorts. After adjusting for clinical covariates, off-pump coronary artery bypass grafting did not emerge as a significant independent predictor of long-term mortality (Hazard Ratio 0.91; 95% Confidence Interval 0.70–1.12), readmission to hospital for cardiac cause (Hazard Ratio 0.96; 95% Confidence Interval 0.78–1.10), or the need for reintervention (Hazard Ratio 0.93; 95% Confidence Interval 0.87–1.05). Off-pump coronary artery bypass grafting compared with on-pump coronary artery bypass grafting does not adversely impact survival or freedom from reintervention at a 10-year follow-up.