Diffusion tensor imaging of lumbar spinal nerve in subjects with degenerative lumbar disorders

• Published in: Magnetic resonance imaging Vol. 33; no. 8; pp. 956 - 961
• Main Authors: Oikawa, Yasuhiro, Eguchi, Yawara, Inoue, Gen, Yamauchi, Kazuyo, Orita, Sumihisa, Kamoda, Hiroto, Ishikawa, Tetsuhiro, Miyagi, Masayuki, Suzuki, Miyako, Sakuma, Yoshihiro, Kubota, Go, Inage, Kazuhide, Saino, Takeshi, Sato, Hirotaka, Ando, Hiroki, Kojima, Masatoshi, Okumura, Kenichiro, Masuda, Yoshitada, Watanabe, Atsuya, Takahashi, Kazuhisa, Ohtori, Seiji
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.10.2015
• Subjects: Adult; Diffusion tensor imaging; Diffusion Tensor Imaging - methods; Feasibility Studies; Female; Fractional anisotropy; Humans; Image Enhancement - methods; Image Interpretation, Computer-Assisted - methods; Intervertebral Disc Degeneration - complications; Intervertebral Disc Degeneration - pathology; Lumbar spinal stenosis; Lumbar Vertebrae - innervation; Lumbar Vertebrae - pathology; Magnetic resonance imaging; Male; Middle Aged; Radiology; Reproducibility of Results; Sciatica - etiology; Sciatica - pathology; Sensitivity and Specificity; Spinal Nerves - pathology; Spinal Stenosis - complications; Spinal Stenosis - pathology; Fractional anisotropy; Magnetic resonance imaging; Lumbar spinal stenosis; Diffusion tensor imaging
• ISSN: 0730-725X; 1873-5894; 1873-5894
• DOI: 10.1016/j.mri.2015.05.002

Recently several authors have reported that diffusion tensor imaging (DTI) might provide a new understanding of sciatica. The purpose of this study was to investigate the clinical feasibility of DTI for the evaluation of lumbar spinal nerve of patients with sciatica associated with lumbar degenerative disorders. Thirty-four patients (25men, mean age63. 3years) with degenerated lumbar disease, 14 patients with lumbar spinal stenosis with foraminal stenosis, 12 with lumbar spinal stenosis without foraminal stenosis, five with lumbar disc herniation, two with discogenic low back pain, and one with spondylolysis who underwent 3.0T magnetic resonance (MR) imaging and surgical treatment were included in the present study. Fractional anisotropy (FA) was calculated from an FA map, and tractography was investigated. In asymptomatic nerves, tractography showed all L3–S1 spinal nerve roots clearly. Abnormalities of tractography were classified into three types by shape; “Disrupted”, “Narrowing”, and “Tapering”. More abnormalities of tractography were found in patients with lumbar spinal stenosis, and especially in patients with foraminal stenosis. The disrupted type was the most common. The mean FA of entrapped symptomatic nerves was less than seen on the intact side. This study demonstrates that tractography shows abnormal findings for nerve roots in lumbar spinal degeneration and that FA decreases in symptomatic roots. DTI may offer not only morphological evaluation, but also quantitative evaluation. We believe that DTI can be used as a tool for the diagnosis of lumbar spinal degenerative disease.