Endothelial progenitor cells in age-related vascular remodeling

• Published in: Cell transplantation Vol. 27; no. 5; pp. 786 - 795
• Main Authors: Yang, Jin-Xiu, Pan, Yan-Yun, Wang, Xing-Xiang, Qiu, Yuan-Gang, Mao, Wei
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.05.2018; Sage Publications Ltd; SAGE Publishing
• Subjects: Age; Aging - physiology; Animals; Arteries; Endothelial cells; Endothelial Progenitor Cells - physiology; Humans; Models, Biological; Progenitor cells; Reviews; Stem cells; Vascular Remodeling - physiology; vascular remodeling; age; Endothelial progenitor cell

Accumulating evidence has demonstrated that endothelial progenitor cells (EPCs) could facilitate the reendothelialization of injured arteries by replacing the dysfunctional endothelial cells, thereby suppressing the formation of neointima. Meanwhile, other findings suggest that EPCs may be involved...