Adhesion and Invasion of Gastric Mucosa Epithelial Cells by Helicobacter pylori

is the main pathogenic bacterium involved in chronic gastritis and peptic ulcer and a class 1 carcinogen in gastric cancer. Current research focuses on the pathogenicity of and the mechanism by which it colonizes the gastric mucosa. An increasing number of and studies demonstrate that can invade and...

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Published inFrontiers in cellular and infection microbiology Vol. 6; p. 159
Main Authors Huang, Ying, Wang, Qi-long, Cheng, Dan-dan, Xu, Wen-ting, Lu, Nong-hua
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 22.11.2016
Subjects
Adhesion
Animals
Bacterial Adhesion
Chronic infection
Epithelial Cells - microbiology
Gastric Mucosa - microbiology
Helicobacter pylori
Helicobacter pylori - physiology
Humans
invasion
mechanisms
Microbiology
adhesion
Helicobacter pylori
invasion
mechanism
chronic infection
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Summary:is the main pathogenic bacterium involved in chronic gastritis and peptic ulcer and a class 1 carcinogen in gastric cancer. Current research focuses on the pathogenicity of and the mechanism by which it colonizes the gastric mucosa. An increasing number of and studies demonstrate that can invade and proliferate in epithelial cells, suggesting that this process might play an important role in disease induction, immune escape and chronic infection. Therefore, to explore the process and mechanism of adhesion and invasion of gastric mucosa epithelial cells by is particularly important. This review examines the relevant studies and describes evidence regarding the adhesion to and invasion of gastric mucosa epithelial cells by .
Bibliography:Edited by: D. Scott Merrell, Uniformed Services University, USA
Reviewed by: Robert Maier, University of Georgia, USA; Traci Testerman, University of South Carolina, USA
ISSN:2235-2988
2235-2988
DOI:10.3389/fcimb.2016.00159