Impact of Maternal Age on Oocyte and Embryo Competence

• Published in: Frontiers in endocrinology (Lausanne) Vol. 9; p. 327
• Main Authors: Cimadomo, Danilo, Fabozzi, Gemma, Vaiarelli, Alberto, Ubaldi, Nicolò, Ubaldi, Filippo Maria, Rienzi, Laura
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 29.06.2018
• Subjects: aging; aneuploidies; Endocrinology; IVF; oocyte competence; ovarian reserve; IVF; oocyte competence; aging; ovarian reserve; aneuploidies

The overall success of human reproduction, either spontaneously or after IVF, is highly dependent upon maternal age. The main reasons for age-related infertility include reduced ovarian reserve and decreased oocyte/embryo competence due to aging insults, especially concerning an increased incidence...