Clinical and epidemiological characteristics of a young child infected with avian influenza A (H9N2) virus in China

• Published in: Journal of international medical research Vol. 46; no. 8; pp. 3462 - 3467
• Main Authors: Liu, Ruchun, Zhao, Bin, Li, Yelan, Zhang, Xixing, Chen, Shuilian, Chen, Tianmu
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.08.2018; Sage Publications Ltd; SAGE Publishing
• Subjects: Adolescent; Animals; Case Reports; Child, Preschool; China - epidemiology; Environmental Monitoring; Female; Food Industry; Humans; Infant; Influenza; Influenza A Virus, H9N2 Subtype - isolation & purification; Influenza in Birds - diagnosis; Influenza in Birds - epidemiology; Influenza in Birds - transmission; Influenza, Human - diagnosis; Influenza, Human - epidemiology; Influenza, Human - therapy; Influenza, Human - transmission; Male; Poultry - virology; Public Health; Surveillance; Zoonoses - epidemiology; Zoonoses - virology; China; Avian influenza; mild case; poultry; H9N2; children; public health
• ISSN: 0300-0605; 1473-2300
• DOI: 10.1177/0300060518779959

Three cases of the avian influenza A (H9N2) virus have been documented in Changsha, which is a large city that has nine districts and a population of 7.04 million in central South China. Among these patients, one was a girl and two were boys. The ages of the patients were 9 months, 2 years, and 15 years. Two cases of H9N2 were detected in September, 2015 and one was detected in 2017. Two patients were children who had not reached the age for kindergarten and one was a student. These three cases were all mild and were detected in a sentinel hospital of the Chinese Influenza Surveillance System. We describe the clinical and epidemiological features of the youngest patient with H9N2 in 2017 and the surveillance results of the H9N2 virus in live poultry markets in Changsha. From January 2014 to December 2017, 4212 samples were collected in live poultry markets in Changsha, among which 25.81% (1087/4212) were H9N2-positive. Public health concerns should be addressed for emerging H9N2 virus infection, and more strategies should be performed before this virus mutates to be more transmissible and highly pathogenic.