Dermatophytic pseudomycetomas in four cats

• Published in: Veterinary dermatology Vol. 22; no. 2; pp. 181 - 187
• Main Authors: Chang, Shih-Chieh, Liao, Jiunn-Wang, Shyu, Ching-Lin, Hsu, Wei-Li, Wong, Min-Liang
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.04.2011
• Subjects: adipose tissue; administration & dosage; Animals; Antifungal Agents; Antifungal Agents - administration & dosage; Antifungal Agents - therapeutic use; cat diseases; Cat Diseases - diagnosis; Cat Diseases - therapy; Cats; clinical trials; Combined Modality Therapy; Combined Modality Therapy - veterinary; Dermatomycoses; Dermatomycoses - diagnosis; Dermatomycoses - therapy; Dermatomycoses - veterinary; diagnosis; excision; fascia; Female; fistula; fluorescence; hairs; isolation & purification; itraconazole; Itraconazole - administration & dosage; Itraconazole - therapeutic use; lamps; Male; males; Microsporum; Microsporum - isolation & purification; Recurrence; Retrospective Studies; skin lesions; therapeutic use; therapy; Treatment Outcome; veterinary; wood
• ISSN: 0959-4493; 1365-3164; 1365-3164
• DOI: 10.1111/j.1365-3164.2010.00937.x

The aim of this retrospective study was to describe the clinical characteristics and treatment of four cats with dermatophytic pseudomycetoma. Four Persian cats, one female and three males, with age ranging from 1.4 to 5 years, were diagnosed with dermatophytic pseudomycetoma by histological examination and fungal culture. Wood's lamp examination revealed positive fluorescence of hairs in all four cats. Characteristic skin lesions consisted of multifocal, raised, firm and nodular to dome-shaped lesions varying in size from 1 to 8 cm in diameter, with ulcers or fistulas in some of the lesions. One cat was treated and cured with 3 months of oral itraconazole; lesions completely regressed, and at the time of writing there has been no recurrence. One cat was treated with surgical excision alone, and recurrence of lesions occurred after a disease-free interval of 15 months. Two cats were treated with surgical excision and systemic itraconazole therapy. Itraconazole therapy was started 1-2 months before surgery and continued for 3 months after surgery. Surgical margins were wide in both cats, and underlying adipose tissue and/or deeper fascia was removed. One cat relapsed, but had a disease-free interval of 18 months. The other cat has been disease free for 32 months. This case series suggests that aggressive, wide surgical excision and concurrent oral itraconazole are highly beneficial in treating dermatophytic pseudomycetoma in cats.