Effect of dopamine transporter genotype on caudate volume in childhood ADHD and controls

Polymorphism of the dopamine transporter genotype (DAT1) confers a small but significant susceptibility to attention deficit hyperactivity disorder (ADHD). We examined whether the volume of the head of caudate, a striatal structure with high DAT expression that is important for inhibitory function,...

Full description

Saved in:
Bibliographic Details
Published inAmerican journal of medical genetics. Part B, Neuropsychiatric genetics Vol. 156B; no. 1; pp. 28 - 35
Main Authors Shook, Devon, Brady, Colin, Lee, Philip S., Kenealy, Laura, Murphy, Eric R., Gaillard, William D., VanMeter, John W., Cook Jr, Edwin H., Stein, Mark, Vaidya, Chandan J.
Format Journal Article
LanguageEnglish
Published Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.01.2011
Wiley-Liss
Subjects
Adolescent
Attention Deficit Disorder with Hyperactivity - genetics
Attention Deficit Disorder with Hyperactivity - pathology
Attention deficit hyperactivity disorder
Biological and medical sciences
brain
Brain Mapping
Case-Control Studies
Caudate Nucleus - pathology
Child
Children
Demography
Dopamine Plasma Membrane Transport Proteins - genetics
Dopamine transporter
Female
Genotype
Head
Hemispheric laterality
Humans
Intelligence
Male
Medical genetics
Medical sciences
Neostriatum
Organ Size
polymorphism
striatal
structure
VNTR
Human
Brain
striatal
Dopamine
Typing
Biological transport
Check
Genotype
Catecholamine
Encephalon
Volume
Neurotransmitter
Structure
Child
VNTR
Polymorphism
Online AccessGet full text

Cover

Abstract Polymorphism of the dopamine transporter genotype (DAT1) confers a small but significant susceptibility to attention deficit hyperactivity disorder (ADHD). We examined whether the volume of the head of caudate, a striatal structure with high DAT expression that is important for inhibitory function, differs by DAT1 in children diagnosed with the disorder relative to age and IQ matched controls. Volume of the head of caudate was delineated in the right and left hemisphere and compared between 7‐ and 13‐year‐old children with and without ADHD (combined type) who were carriers of two (10/10) or one (9/10) copy of the 10‐repeat DAT1 allele. Caudate volumes were overall smaller in 10/10 than 9/10 children, particularly in the left than right hemisphere. While DAT1 effects did not vary by ADHD diagnosis, overall caudate volumes were smaller in ADHD relative to control children. Altered caudate development associated with 10‐repeat homozygosity of DAT1 may contribute susceptibility to ADHD. © 2010 Wiley‐Liss, Inc.
AbstractList Polymorphism of the dopamine transporter genotype (DAT1) confers a small but significant susceptibility to attention deficit hyperactivity disorder (ADHD). We examined whether the volume of the head of caudate, a striatal structure with high DAT expression that is important for inhibitory function, differs by DAT1 in children diagnosed with the disorder relative to age and IQ matched controls. Volume of the head of caudate was delineated in the right and left hemisphere and compared between 7‐ and 13‐year‐old children with and without ADHD (combined type) who were carriers of two (10/10) or one (9/10) copy of the 10‐repeat DAT1 allele. Caudate volumes were overall smaller in 10/10 than 9/10 children, particularly in the left than right hemisphere. While DAT1 effects did not vary by ADHD diagnosis, overall caudate volumes were smaller in ADHD relative to control children. Altered caudate development associated with 10‐repeat homozygosity of DAT1 may contribute susceptibility to ADHD. © 2010 Wiley‐Liss, Inc.
Polymorphism of the dopamine transporter genotype (DAT1) confers a small but significant susceptibility to attention deficit hyperactivity disorder (ADHD). We examined whether the volume of the head of caudate, a striatal structure with high DAT expression that is important for inhibitory function, differs by DAT1 in children diagnosed with the disorder relative to age and IQ matched controls. Volume of the head of caudate was delineated in the right and left hemisphere and compared between 7- and 13-year-old children with and without ADHD (combined type) who were carriers of two (10/10) or one (9/10) copy of the 10-repeat DAT1 allele. Caudate volumes were overall smaller in 10/10 than 9/10 children, particularly in the left than right hemisphere. While DAT1 effects did not vary by ADHD diagnosis, overall caudate volumes were smaller in ADHD relative to control children. Altered caudate development associated with 10-repeat homozygosity of DAT1 may contribute susceptibility to ADHD. copyright 2010 Wiley-Liss, Inc.
Polymorphism of the dopamine transporter genotype (DAT1) confers a small but significant susceptibility to attention deficit hyperactivity disorder (ADHD). We examined whether the volume of the head of caudate, a striatal structure with high DAT expression that is important for inhibitory function, differs by DAT1 in children diagnosed with the disorder relative to age and IQ matched controls. Volume of the head of caudate was delineated in the right and left hemisphere and compared between 7- and 13-year-old children with and without ADHD (combined type) who were carriers of two (10/10) or one (9/10) copy of the 10-repeat DAT1 allele. Caudate volumes were overall smaller in 10/10 than 9/10 children, particularly in the left than right hemisphere. While DAT1 effects did not vary by ADHD diagnosis, overall caudate volumes were smaller in ADHD relative to control children. Altered caudate development associated with 10-repeat homozygosity of DAT1 may contribute susceptibility to ADHD.
Abstract Polymorphism of the dopamine transporter genotype (DAT1) confers a small but significant susceptibility to attention deficit hyperactivity disorder (ADHD). We examined whether the volume of the head of caudate, a striatal structure with high DAT expression that is important for inhibitory function, differs by DAT1 in children diagnosed with the disorder relative to age and IQ matched controls. Volume of the head of caudate was delineated in the right and left hemisphere and compared between 7‐ and 13‐year‐old children with and without ADHD (combined type) who were carriers of two (10/10) or one (9/10) copy of the 10‐repeat DAT1 allele. Caudate volumes were overall smaller in 10/10 than 9/10 children, particularly in the left than right hemisphere. While DAT1 effects did not vary by ADHD diagnosis, overall caudate volumes were smaller in ADHD relative to control children. Altered caudate development associated with 10‐repeat homozygosity of DAT1 may contribute susceptibility to ADHD. © 2010 Wiley‐Liss, Inc.
Author Vaidya, Chandan J.
Shook, Devon
Gaillard, William D.
Lee, Philip S.
Brady, Colin
Kenealy, Laura
Cook Jr, Edwin H.
Stein, Mark
Murphy, Eric R.
VanMeter, John W.
AuthorAffiliation 1 Department of Psychology, Georgetown University, Washington DC
3 Center for Functional and Molecular Imaging, Georgetown University Medical Center, Washington, DC
2 Center for Neuroscience, Children’s National Medical Center, Washington, DC
4 Department of Psychiatry, University of Illinois at Chicago, Chicago, IL
AuthorAffiliation_xml – name: 1 Department of Psychology, Georgetown University, Washington DC
– name: 3 Center for Functional and Molecular Imaging, Georgetown University Medical Center, Washington, DC
– name: 4 Department of Psychiatry, University of Illinois at Chicago, Chicago, IL
– name: 2 Center for Neuroscience, Children’s National Medical Center, Washington, DC
Author_xml – sequence: 1
  givenname: Devon
  surname: Shook
  fullname: Shook, Devon
  organization: Department of Psychology, Georgetown University, Washington District of Columbia
– sequence: 2
  givenname: Colin
  surname: Brady
  fullname: Brady, Colin
  organization: Department of Psychology, Georgetown University, Washington District of Columbia
– sequence: 3
  givenname: Philip S.
  surname: Lee
  fullname: Lee, Philip S.
  organization: Department of Psychology, Georgetown University, Washington District of Columbia
– sequence: 4
  givenname: Laura
  surname: Kenealy
  fullname: Kenealy, Laura
  organization: Center for Neuroscience, Children's National Medical Center, Washington, District of Columbia
– sequence: 5
  givenname: Eric R.
  surname: Murphy
  fullname: Murphy, Eric R.
  organization: Department of Psychology, Georgetown University, Washington District of Columbia
– sequence: 6
  givenname: William D.
  surname: Gaillard
  fullname: Gaillard, William D.
  organization: Center for Neuroscience, Children's National Medical Center, Washington, District of Columbia
– sequence: 7
  givenname: John W.
  surname: VanMeter
  fullname: VanMeter, John W.
  organization: Center for Functional and Molecular Imaging, Georgetown University Medical Center, Washington, District of Columbia
– sequence: 8
  givenname: Edwin H.
  surname: Cook Jr
  fullname: Cook Jr, Edwin H.
  organization: Department of Psychiatry, University of Ilinois at Chicago, Chicago, IL
– sequence: 9
  givenname: Mark
  surname: Stein
  fullname: Stein, Mark
  organization: Department of Psychiatry, University of Ilinois at Chicago, Chicago, IL
– sequence: 10
  givenname: Chandan J.
  surname: Vaidya
  fullname: Vaidya, Chandan J.
  email: cjv2@georgetown.edu
  organization: Department of Psychology, Georgetown University, Washington District of Columbia
BackLink http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23784322$$DView record in Pascal Francis
https://www.ncbi.nlm.nih.gov/pubmed/20957668$$D View this record in MEDLINE/PubMed
BookMark eNp9kc9v0zAUxy00xLbCjTPyBcFhKf4Rx8kFqdpGCxpDQgMmLpZjO61HYgc72eh_j0u7Aped_OT3ed_vs7_H4MB5ZwB4jtEUI0TeyJtuOa2nFGNKHoEjzBjJ8pJdH-zrHB-C4xhvEKKIcf4EHBJUMV4U5RG4Pm8aowboG6h9LzvrDByCdLH3YTABLo3zw7o30Duo5KjlYOCtb8fOQJtuVrbVK-81nJ0tzqB0GirvhuDb-BQ8bmQbzbPdOQFf3p1fnS6yi0_z96ezi0wxUpJMF7SuDa9ojkhdVrxQRFWsKgmtqaEkJ5VGdV7rhkvGckowYZpzkgqdN4XWdALebnX7se6MVibZy1b0wXYyrIWXVvzfcXYllv5WUIQRqcok8GonEPzP0cRBdDYq07bSGT9GURKMqxIxnMjXD5IYYV5xjNKeE3CyRVXwMQbT7BfCSGxiE5vYRC3-xJbwF_8-Yg_f55SAlztARiXbJiWkbPzLUV6mz9kI0S13Z1uzftBUzD58nN_bZ9spGwfzaz8lww9RcMqZ-HY5F1_J4vvV5wKJS_obMq_BxQ
CitedBy_id crossref_primary_10_1016_j_jaac_2016_06_013
crossref_primary_10_1007_s11920_014_0497_1
crossref_primary_10_1016_j_biopsych_2013_08_013
crossref_primary_10_1016_j_bmcl_2012_05_030
crossref_primary_10_1002_ajmg_b_32542
crossref_primary_10_1016_j_rpsm_2015_02_003
crossref_primary_10_3389_fpsyg_2022_751041
crossref_primary_10_1007_s00702_016_1521_x
crossref_primary_10_1002_ajmg_b_32578
crossref_primary_10_3390_ijerph19084479
crossref_primary_10_1016_j_neubiorev_2016_08_017
crossref_primary_10_1007_s11682_016_9663_x
crossref_primary_10_1089_can_2017_0021
crossref_primary_10_1371_journal_pone_0155755
crossref_primary_10_1089_cap_2012_0072
crossref_primary_10_1177_1087054716647483
crossref_primary_10_1007_s12035_014_8683_z
crossref_primary_10_1016_j_rpsmen_2016_01_003
crossref_primary_10_1016_j_jaac_2012_05_006
crossref_primary_10_1016_j_neubiorev_2017_01_013
crossref_primary_10_1016_j_pscychresns_2015_07_005
crossref_primary_10_1038_s41398_021_01473_w
Cites_doi 10.1002/ajmg.b.30453
10.1186/1471-2156-6-55
10.1097/00004583-199703000-00016
10.1016/S0893-133X(99)00099-8
10.1016/S0140-6736(95)90441-7
10.1002/syn.10038
10.1016/j.biopsych.2005.01.034
10.1006/nimg.2000.0651
10.1523/JNEUROSCI.4858-08.2009
10.1093/brain/120.2.257
10.1016/j.biopsych.2004.10.011
10.1001/archpsyc.64.8.921
10.1016/j.euroneuro.2004.06.004
10.1186/1471-244X-8-51
10.1038/sj.mp.4001641
10.1016/j.biopsych.2004.11.019
10.1016/S0301-0082(02)00011-4
10.1212/01.wnl.0000237385.84037.3c
10.1176/ajp.151.10.1430
10.1038/sj.mp.4001649
10.1177/088307380201700202
10.1016/j.neuroimage.2008.10.055
10.1002/ddrr.40
10.1002/ajmg.b.30107
10.1016/j.biopsych.2005.03.036
10.1038/sj.tpj.6500026
10.2967/jnumed.108.053652
10.1007/s00439-009-0694-x
10.1016/j.neuroimage.2004.07.051
10.1038/sj.mp.4000921
10.1006/nimg.2000.0582
10.1097/00004583-200004000-00017
10.2174/1573405054038726
10.1176/ajp.151.12.1791
10.1001/archneur.1997.00550200027006
10.1177/088307389300800409
10.1080/15622970500518444
10.1097/01.CHI.0000046890.27264.88
10.1001/archpsyc.1996.01830070053009
10.1002/ajmg.b.10948
10.1001/jama.288.14.1740
10.1006/nimg.2002.1174
10.1007/978-3-7091-6792-2
10.1016/S0893-133X(00)00216-5
10.1086/302132
10.1016/j.biopsych.2008.02.001
10.1176/appi.ajp.157.10.1700
10.1097/chi.0b013e31815a5f17
10.1016/j.biopsych.2006.06.011
10.1212/WNL.48.3.589
ContentType Journal Article
Copyright Copyright © 2010 Wiley‐Liss, Inc.
2015 INIST-CNRS
Copyright © 2010 Wiley-Liss, Inc.
Copyright_xml – notice: Copyright © 2010 Wiley‐Liss, Inc.
– notice: 2015 INIST-CNRS
– notice: Copyright © 2010 Wiley-Liss, Inc.
DBID BSCLL
IQODW
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
7TK
8FD
FR3
P64
RC3
7X8
5PM
DOI 10.1002/ajmg.b.31132
DatabaseName Istex
Pascal-Francis
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
CrossRef
Neurosciences Abstracts
Technology Research Database
Engineering Research Database
Biotechnology and BioEngineering Abstracts
Genetics Abstracts
MEDLINE - Academic
PubMed Central (Full Participant titles)
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
CrossRef
Genetics Abstracts
Engineering Research Database
Technology Research Database
Neurosciences Abstracts
Biotechnology and BioEngineering Abstracts
MEDLINE - Academic
DatabaseTitleList
Genetics Abstracts
MEDLINE
CrossRef
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Biology
EISSN 1552-485X
EndPage 35
ExternalDocumentID 10_1002_ajmg_b_31132
20957668
23784322
AJMG31132
ark_67375_WNG_V2HZTR60_N
Genre article
Journal Article
Research Support, N.I.H., Extramural
GrantInformation_xml – fundername: NIMH
  funderid: MH065395; MH70564
– fundername: NIMH NIH HHS
  grantid: R01 MH065395
– fundername: NIMH NIH HHS
  grantid: MH70564
– fundername: NIMH NIH HHS
  grantid: R01 MH065395-05
– fundername: NIMH NIH HHS
  grantid: R01 MH070564
– fundername: NIMH NIH HHS
  grantid: MH065395
– fundername: NIMH NIH HHS
  grantid: R01 MH070564-06
GroupedDBID .55
.GA
.Y3
05W
10A
1L6
1OC
23M
31~
33P
4.4
51W
51X
52N
52O
52P
52S
52T
52W
52X
53G
5GY
5VS
7PT
8-1
8-4
8-5
8UM
AAEVG
AAHHS
AANLZ
AAONW
AASGY
AAXRX
AAZKR
ABCQN
ABCUV
ABEML
ABHUG
ABIJN
ABIVO
ABJNI
ABWRO
ACAHQ
ACBWZ
ACCFJ
ACCZN
ACFBH
ACGFO
ACGFS
ACPOU
ACPRK
ACSCC
ACXBN
ACXME
ACXQS
ADAWD
ADDAD
ADEOM
ADIZJ
ADKYN
ADMGS
ADOZA
ADZMN
ADZOD
AEEZP
AEIGN
AEIMD
AEQDE
AEQTP
AEUQT
AEUYR
AFBPY
AFFPM
AFGKR
AFPWT
AFVGU
AFZJQ
AGJLS
AHBTC
AIAGR
AIURR
AIWBW
AJBDE
ALMA_UNASSIGNED_HOLDINGS
ALUQN
AMBMR
AMYDB
ASPBG
ATUGU
AVWKF
AZBYB
AZFZN
BDRZF
BFHJK
BRXPI
BSCLL
BY8
C45
CS3
D-F
DCZOG
DPXWK
DR2
DRFUL
DRSTM
EBD
EBS
EJD
EMOBN
F00
F01
F04
F5P
FEDTE
G-S
GNP
GODZA
HBH
HF~
HHY
HHZ
HVGLF
IX1
KQQ
LATKE
LAW
LEEKS
LH4
LOXES
LP6
LP7
LUTES
LYRES
MEWTI
MRFUL
MRSTM
MSFUL
MSSTM
MXFUL
MXSTM
OVD
P2P
P2W
P4D
QB0
QRW
ROL
RWI
SUPJJ
SV3
TEORI
UB1
V2E
W99
WIH
WJL
WQJ
WRC
WXSBR
X7M
XG1
XV2
0R~
AITYG
HGLYW
OIG
08R
AAUGY
IQODW
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
7TK
8FD
FR3
P64
RC3
7X8
5PM
ID FETCH-LOGICAL-c5282-d63bbe793402b8976c2c959823b3e32429d0b4bdf7a55432125d772321d4f6dd3
IEDL.DBID DR2
ISSN 1552-4841
1552-485X
IngestDate Tue Sep 17 20:54:06 EDT 2024
Fri Aug 16 01:14:09 EDT 2024
Fri Aug 16 05:16:37 EDT 2024
Fri Aug 23 03:41:11 EDT 2024
Sat Sep 28 07:57:50 EDT 2024
Sun Oct 22 16:03:16 EDT 2023
Sat Aug 24 00:57:09 EDT 2024
Wed Jan 17 05:00:09 EST 2024
IsDoiOpenAccess false
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 1
Keywords Human
Brain
striatal
Dopamine
Typing
Biological transport
Check
Genotype
Catecholamine
Encephalon
Volume
Neurotransmitter
Structure
Child
VNTR
Polymorphism
Language English
License CC BY 4.0
Copyright © 2010 Wiley-Liss, Inc.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c5282-d63bbe793402b8976c2c959823b3e32429d0b4bdf7a55432125d772321d4f6dd3
Notes NIMH - No. MH065395; No. MH70564
ark:/67375/WNG-V2HZTR60-N
istex:177FA07503C5BCDB33F815F3E0A7D55BEC2C1CD6
ArticleID:AJMG31132
How to Cite this Article: Shook D, Brady C, Lee PS, Kenealy L, Murphy ER, Gaillard WD, VanMeter JW, Cook E, Stein M, Vaidya CJ. 2011. Effect of Dopamine Transporter Genotype on Caudate Volume in Childhood ADHD and Controls. Am J Med Genet Part B 156:28-35.
How to Cite this Article: Shook D, Brady C, Lee PS, Kenealy L, Murphy ER, Gaillard WD, VanMeter JW, Cook E, Stein M, Vaidya CJ. 2011. Effect of Dopamine Transporter Genotype on Caudate Volume in Childhood ADHD and Controls. Am J Med Genet Part B 156:28–35.
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ObjectType-Article-1
ObjectType-Feature-2
OpenAccessLink https://europepmc.org/articles/pmc3010298?pdf=render
PMID 20957668
PQID 1017971054
PQPubID 23462
PageCount 8
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_3010298
proquest_miscellaneous_821198051
proquest_miscellaneous_1017971054
crossref_primary_10_1002_ajmg_b_31132
pubmed_primary_20957668
pascalfrancis_primary_23784322
wiley_primary_10_1002_ajmg_b_31132_AJMG31132
istex_primary_ark_67375_WNG_V2HZTR60_N
PublicationCentury 2000
PublicationDate January 2011
PublicationDateYYYYMMDD 2011-01-01
PublicationDate_xml – month: 01
  year: 2011
  text: January 2011
PublicationDecade 2010
PublicationPlace Hoboken
PublicationPlace_xml – name: Hoboken
– name: Hoboken, NJ
– name: United States
PublicationTitle American journal of medical genetics. Part B, Neuropsychiatric genetics
PublicationTitleAlternate Am. J. Med. Genet
PublicationYear 2011
Publisher Wiley Subscription Services, Inc., A Wiley Company
Wiley-Liss
Publisher_xml – name: Wiley Subscription Services, Inc., A Wiley Company
– name: Wiley-Liss
References Mill J, Xu X, Ronald A, Curran S, Price T, Knight J, Craig I, Sham P, Plomin R, Asherson P. 2005. Quantitative trait locus analysis of candidate gene alleles associated with attention deficit hyperactivity disorder (ADHD) in five genes: DRD4, DAT1, DRD5, SNAP-25, and 5HT1B. Am J Med Genet Part B 133B(1): 68-73.
DuPaul GJ, Power TJ, Anastopoulos AD, Reid R. 1998. ADHD-Rating Scales DSM-IV for parents and teachers. New York: Guilford.
Reynolds CR, Kamphaus RW, editors. 1998. Behavior assessment system for children. Circle Pines, MN: American Guidance Service.
Bartley AJ, Jones DW, Weinberger DR. 1997. Genetic variability of human brain size and cortical gyral patterns. Brain 120(Pt 2): 257-269.
Burgund ED, Kang HC, Kelly JE, Buckner RL, Snyder AZ, Petersen SE, Schlaggar BL. 2002. The feasibility of a common stereotactic space for children and adults in fMRI studies of development. Neuroimage 17(1): 184-200.
Heinz A, Goldman D, Jones DW, Palmour R, Hommer D, Gorey JG, Lee KS, Linnoila M, Weinberger DR. 2000. Genotype influences in vivo dopamine transporter availability in human striatum. Neuropsychopharmacology 22(2): 133-139.
Vaidya CJ, Stollstorff M. 2008. Cognitive neuroscience of attention deficit hyperactivity disorder: Current status and working hypotheses. Dev Disabil Res Rev 14(4): 261-267.
Castellanos FX, Giedd JN, Marsh WL, Hamburger SD, Vaituzis AC, Dickstein DP, et al. 1996. Quantitative brain magnetic resonance imaging in attention-deficit hyperactivity disorder. Arch Gen Psychiatry 53(7): 607-616.
Semrud-Clikeman M, Pliszka SR, Lancaster J, Liotti M. 2006. Volumetric MRI differences in treatment-naive vs chronically treated children with ADHD. Neurology 67(6): 1023-1027.
Martinez D, Gelernter J, Abi-Dargham A, van Dyck CH, Kegeles L, Innis RB, Laruelle M. 2001. The variable number of tandem repeats polymorphism of the dopamine transporter gene is not associated with significant change in dopamine transporter phenotype in humans. Neuropsychopharmacology 24(5): 553-560.
Yang B, Chan RC, Jing J, Li T, Sham P, Chen RY. 2007. A meta-analysis of association studies between the 10-repeat allele of a VNTR polymorphism in the 3′-UTR of dopamine transporter gene and attention deficit hyperactivity disorder. Am J Med Genet Part B 144B(4): 541-550.
Castellanos FX, Lee PP, Sharp W, Jeffries NO, Greenstein DK, Clasen LS, Blumenthal JD, James RS, Ebens CL, Walter JM, et al. 2002. Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorder. JAMA 288(14): 1740-1748.
Bush G, Valera EM, Seidman LJ. 2005. Functional neuroimaging of attention-deficit/hyperactivity disorder: A review and suggested future directions. Biol Psychiatry 57(11): 1273-1284.
Mechelli A, Price CJ, Friston KJ, Ashburner J. 2005. Voxel-based morphometry of the human brain: Methods and applications. Curr Med Imaging Rev 1(1): 105-113.
Nieoullon A. 2002. Dopamine and the regulation of cognition and attention. Prog Neurobiol 67(1): 53-83.
Loo SK, Specter E, Smolen A, Hopfer C, Teale PD, Reite ML. 2003. Functional effects of the DAT1 polymorphism on EEG measures in ADHD. J Am Acad Child Adolesc Psychiatry 42(8): 986-993.
Woolrich MW, Jbabdi S, Patenaude B, Chappell M, Makni S, Behrens T, Beckmann C, Jenkinson M, Smith SM. 2009. Bayesian analysis of neuroimaging data in FSL. Neuroimage 45(1 Suppl): S173-S186.
Miller GM, Madras BK. 2002. Polymorphisms in the 3′-untranslated region of human and monkey dopamine transporter genes affect reporter gene expression. Mol Psychiatry 7(1): 44-55.
Chakos MH, Lieberman JA, Bilder RM, Borenstein M, Lerner G, Bogerts B, Wu H, Kinon B, Ashtari M. 1994. Increase in caudate nuclei volumes of first-episode schizophrenic patients taking antipsychotic drugs. Am J Psychiatry 151(10): 1430-1436.
Waldman ID, Rowe DC, Abramowitz A, Kozel ST, Mohr JH, Sherman SL, Cleveland HH, Sanders ML, Gard JM, Stever C. 1998. Association and linkage of the dopamine transporter gene and attention-deficit hyperactivity disorder in children: Heterogeneity owing to diagnostic subtype and severity. Am J Hum Genet 63(6): 1767-1776.
Semrud-Clikeman M, Steingard RJ, Filipek P, Biederman J, Bekken K, Renshaw PF, 2000. Using MRI to examine brain-behavior relationships in males with attention deficit disorder with hyperactivity. J Am Acad Child Adolesc Psychiatry 39(4): 477-484.
Shaw P, Gornick M, Lerch J, Addington A, Seal J, Greenstein D, Sharp W, Evans A, Giedd JN, Castellanos FX, et al. 2007. Polymorphisms of the dopamine D4 receptor, clinical outcome, and cortical structure in attention-deficit/hyperactivity disorder. Arch Gen Psychiatry 64(8): 921-931.
Spencer TJ, Biederman J, Madras BK, Faraone SV, Dougherty DD, Bonab AA, Fischman AJ. 2005. In vivo neuroreceptor imaging in attention-deficit/hyperactivity disorder: A focus on the dopamine transporter. Biol Psychiatry 57(11): 1293-1300.
VanNess SH, Owens MJ, Kilts CD. 2005. The variable number of tandem repeats element in DAT1 regulates in vitro dopamine transporter density. BMC Genet 6:55.
Cornish KM, Manly T, Savage R, Swanson J, Morisano D, Butler N, Grant C, Cross G, Bentley L, Hollis CP. 2005. Association of the dopamine transporter (DAT1) 10/10-repeat genotype with ADHD symptoms and response inhibition in a general population sample. Mol Psychiatry 10(7): 686-698.
Bertolino A, Fazio L, Di Giorgio A, Blasi G, Romano R, Taurisano P, Caforio G, Sinibaldi L, Ursini G, Popolizio T, et al. 2009. Genetically determined interaction between the dopamine transporter and the D2 receptor on prefronto-striatal activity and volume in humans. J Neurosci 29(4): 1224-1234.
Durston S, Fossella JA, Mulder MJ, Casey BJ, Ziermans TB, Vessaz MN, Van Engeland H. 2008. Dopamine transporter genotype conveys familial risk of attention-deficit/hyperactivity disorder through striatal activation. J Am Acad Child Adolesc Psychiatry 47(1): 61-67.
van Dyck CH, Malison RT, Jacobsen LK, Seibyl JP, Staley JK, Laruelle M, Baldwin RM, Innis RB, Gelernter J. 2005. Increased dopamine transporter availability associated with the 9-repeat allele of the SLC6A3 gene. J Nucl Med 46(5): 745-751.
van de Giessen EM, de Win MM, Tanck MW, van den Brink W, Baas F, Booij J. 2009. Striatal dopamine transporter availability associated with polymorphisms in the dopamine transporter gene SLC6A3. J Nucl Med 50(1): 45-52.
Filipek PA, Semrud-Clikeman M, Steingard RJ, Renshaw PF, Kennedy DN, Biederman J. 1997. Volumetric MRI analysis comparing subjects having attention-deficit hyperactivity disorder with normal controls. Neurology 48(3): 589-601.
Gizer IR, Ficks C, Waldman ID. 2009. Candidate gene studies of ADHD: A meta-analytic review. Hum Genet 126(1): 51-90.
Madras BK, Miller GM, Fischman AJ. 2005. The dopamine transporter and attention-deficit/hyperactivity disorder. Biol Psychiatry 57(11): 1397-1409.
Krause J, Dresel SH, Krause KH, La Fougere C, Zill P, Ackenheil M. 2006. Striatal dopamine transporter availability and DAT-1 gene in adults with ADHD: No higher DAT availability in patients with homozygosity for the 10-repeat allele. World J Biol Psychiatry 7(3): 152-157.
Muzik O, Chugani DC, Juhasz C, Shen C, Chugani HT. 2000. Statistical parametric mapping: Assessment of application in children. Neuroimage 12(5): 538-549.
Cook EH Jr, Stein MA, Krasowski MD, Cox NJ, Olkon DM, Kieffer JE, Leventhal BL. 1995. Association of attention-deficit disorder and the dopamine transporter gene. Am J Hum Genet 56(4): 993-998.
Hynd GW, Hern KL, Novey ES, Eliopulos D, Marshall R, Gonzalez JJ, et al. 1993. Attention deficit-hyperactivity disorder and asymmetry of the caudate nucleus. J Child Neurol 8(4): 339-347.
Pineda DA, Restrepo MA, Sarmiento RJ, Gutierrez JE, Vargas SA, Quiroz YT, et al. 2002. Statistical analyses of structural magnetic resonance imaging of the head of the caudate nucleus in Colombian children with attention-deficit hyperactivity disorder. J Child Neurol 17(2): 97-105.
Chakos MH, Lieberman JA, Alvir J, Bilder R, Ashtari M. 1995. Caudate nuclei volumes in schizophrenic patients treated with typical antipsychotics or clozapine. Lancet 345(8947): 456-457.
Mataro M, Garcia-Sanchez C, Junque C, Estevez-Gonzalez A, Pujol J. 1997. Magnetic resonance imaging measurement of the caudate nucleus in adolescents with attention-deficit hyperactivity disorder and its relationship with neuropsychological and behavioral measures. Arch Neurol 54(8): 963-968.
Volkow ND, Wang GJ, Fowler JS, Logan J, Franceschi D, Maynard L, Ding YS, Gatley SJ, Gifford A, Zhu W, et al. 2002. Relationship between blockade of dopamine transporters by oral methylphenidate and the increases in extracellular dopamine: Therapeutic implications. Synapse 43(3): 181-187.
Castellanos FX, Giedd JN, Eckburg P, Marsh WL, Vaituzis AC, Kaysen D, et al. 1994. Quantitative morphology of the caudate nucleus in attention deficit hyperactivity disorder. Am J Psychiatry 151(12): 1791-1796.
Mill J, Asherson P, Browes C, D'Souza U, Craig I. 2002. Expression of the dopamine transporter gene is regulated by the 3' UTR VNTR: Evidence from brain and lymphocytes using quantitative RT-PCR. Am J Med Genet 114(8): 975-979.
Smith SM, Jenkinson M, Woolrich MW, Beckmann CF, Behrens TE, Johansen-Berg H, Bannister PR, De Luca M, Drobnjak I, Flitney DE, et al. 2004. Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage 23(Suppl 1): S208-S219.
Ashburner J, Friston KJ. 2000. Voxel-based morphometry-The methods. Neuroimage 11(6 Pt 1): 805-821.
Durston S, Fossella JA, Casey BJ, Hulshoff Pol HE, Galvan A, Schnack HG, Steenhuis MP, Minderaa RB, Buitelaar JK, Kahn RS, et al. 2005. Differential effects of DRD4 and DAT1 genotype on fronto-striatal gray matter volumes in a sample of subjects with attention deficit hyperactivity disorder, their unaffected siblings, and controls. Mol Psychiatry 10(7): 678-685.
Seidman LJ, Valera EM, Makris N. 2005. Structural brain imaging of attention-deficit/hyperactivity disorder. Biol Psychiatry 57(11): 1263-1272.
Duvernoy
2009; 45
2002; 17
1993; 8
2000; 157
1997; 48
1995; 56
2000; 22
2002; 114
2005; 133B
2002; 7
2004; 23
1994; 151
1998
2006; 7
2008; 14
2008; 8
1998; 63
2007; 144B
2001; 24
1996; 53
2009; 29
2005; 46
1999
2000; 39
2006; 67
1997; 54
2000; 12
2009; 50
1997; 120
2002; 67
2000; 11
1997; 36
2002; 43
2002; 288
2008; 47
2005; 10
2005; 6
1995; 345
2005; 1
2007; 61
2001; 1
2008; 64
2005; 15
2007; 64
2003; 42
2009; 126
2005; 57
10649826 - Neuropsychopharmacology. 2000 Feb;22(2):133-9
7717410 - Am J Hum Genet. 1995 Apr;56(4):993-8
19072750 - Dev Disabil Res Rev. 2008;14(4):261-7
19091889 - J Nucl Med. 2009 Jan;50(1):45-52
15578613 - Am J Med Genet B Neuropsychiatr Genet. 2005 Feb 5;133B(1):68-73
11911442 - Pharmacogenomics J. 2001;1(2):152-6
15949998 - Biol Psychiatry. 2005 Jun 1;57(11):1263-72
9837830 - Am J Hum Genet. 1998 Dec;63(6):1767-76
11034861 - Neuroimage. 2000 Nov;12(5):538-49
19059349 - Neuroimage. 2009 Mar;45(1 Suppl):S173-86
15501092 - Neuroimage. 2004;23 Suppl 1:S208-19
11793423 - Synapse. 2002 Mar 1;43(3):181-7
17000972 - Neurology. 2006 Sep 26;67(6):1023-7
15950014 - Biol Psychiatry. 2005 Jun 1;57(11):1397-409
18174826 - J Am Acad Child Adolesc Psychiatry. 2008 Jan;47(1):61-7
10860804 - Neuroimage. 2000 Jun;11(6 Pt 1):805-21
16861140 - World J Biol Psychiatry. 2006;7(3):152-7
15950001 - Biol Psychiatry. 2005 Jun 1;57(11):1293-300
9055518 - J Am Acad Child Adolesc Psychiatry. 1997 Mar;36(3):374-83
17679637 - Arch Gen Psychiatry. 2007 Aug;64(8):921-31
11007732 - Am J Psychiatry. 2000 Oct;157(10):1700-3
18590567 - BMC Psychiatry. 2008;8:51
18374902 - Biol Psychiatry. 2008 Aug 1;64(3):226-34
16309561 - BMC Genet. 2005;6:55
12126656 - Prog Neurobiol. 2002 May;67(1):53-83
9117373 - Brain. 1997 Feb;120 ( Pt 2):257-69
15572278 - Eur Neuropsychopharmacol. 2005 Jan;15(1):95-101
12874502 - J Am Acad Child Adolesc Psychiatry. 2003 Aug;42(8):986-93
7853978 - Lancet. 1995 Feb 18;345(8947):456-7
12457396 - Am J Med Genet. 2002 Dec 8;114(8):975-9
16950217 - Biol Psychiatry. 2007 Jun 15;61(12):1361-9
15809660 - Mol Psychiatry. 2005 Jul;10(7):686-98
15949999 - Biol Psychiatry. 2005 Jun 1;57(11):1273-84
19176830 - J Neurosci. 2009 Jan 28;29(4):1224-34
19506906 - Hum Genet. 2009 Jul;126(1):51-90
15872345 - J Nucl Med. 2005 May;46(5):745-51
11803445 - Mol Psychiatry. 2002;7(1):44-55
7916539 - Am J Psychiatry. 1994 Oct;151(10):1430-6
15724142 - Mol Psychiatry. 2005 Jul;10(7):678-85
12365958 - JAMA. 2002 Oct 9;288(14):1740-8
11282255 - Neuropsychopharmacology. 2001 May;24(5):553-60
12482076 - Neuroimage. 2002 Sep;17(1):184-200
17440978 - Am J Med Genet B Neuropsychiatr Genet. 2007 Jun 5;144B(4):541-50
e_1_2_6_51_1
e_1_2_6_53_1
Cook EH (e_1_2_6_15_1) 1995; 56
e_1_2_6_32_1
e_1_2_6_30_1
e_1_2_6_19_1
e_1_2_6_13_1
e_1_2_6_36_1
e_1_2_6_11_1
e_1_2_6_34_1
e_1_2_6_55_1
e_1_2_6_38_1
e_1_2_6_43_1
e_1_2_6_41_1
e_1_2_6_9_1
e_1_2_6_5_1
e_1_2_6_7_1
e_1_2_6_24_1
e_1_2_6_49_1
e_1_2_6_3_1
e_1_2_6_22_1
e_1_2_6_28_1
e_1_2_6_45_1
e_1_2_6_26_1
e_1_2_6_47_1
Duvernoy HM (e_1_2_6_20_1) 1999
e_1_2_6_52_1
e_1_2_6_54_1
e_1_2_6_10_1
e_1_2_6_31_1
van Dyck CH (e_1_2_6_50_1) 2005; 46
Reynolds CR (e_1_2_6_40_1) 1998
e_1_2_6_14_1
e_1_2_6_35_1
e_1_2_6_12_1
e_1_2_6_33_1
e_1_2_6_18_1
e_1_2_6_39_1
e_1_2_6_16_1
e_1_2_6_37_1
e_1_2_6_42_1
e_1_2_6_21_1
e_1_2_6_8_1
e_1_2_6_4_1
DuPaul GJ (e_1_2_6_17_1) 1998
e_1_2_6_6_1
e_1_2_6_25_1
e_1_2_6_48_1
e_1_2_6_23_1
e_1_2_6_2_1
e_1_2_6_29_1
e_1_2_6_44_1
e_1_2_6_27_1
e_1_2_6_46_1
References_xml – volume: 67
  start-page: 1023
  issue: 6
  year: 2006
  end-page: 1027
  article-title: Volumetric MRI differences in treatment‐naive vs chronically treated children with ADHD
  publication-title: Neurology
– volume: 144B
  start-page: 541
  issue: 4
  year: 2007
  end-page: 550
  article-title: A meta‐analysis of association studies between the 10‐repeat allele of a VNTR polymorphism in the 3′‐UTR of dopamine transporter gene and attention deficit hyperactivity disorder
  publication-title: Am J Med Genet Part B
– volume: 114
  start-page: 975
  issue: 8
  year: 2002
  end-page: 979
  article-title: Expression of the dopamine transporter gene is regulated by the 3' UTR VNTR: Evidence from brain and lymphocytes using quantitative RT‐PCR
  publication-title: Am J Med Genet
– volume: 53
  start-page: 607
  issue: 7
  year: 1996
  end-page: 616
  article-title: Quantitative brain magnetic resonance imaging in attention‐deficit hyperactivity disorder
  publication-title: Arch Gen Psychiatry
– volume: 57
  start-page: 1263
  issue: 11
  year: 2005
  end-page: 1272
  article-title: Structural brain imaging of attention‐deficit/hyperactivity disorder
  publication-title: Biol Psychiatry
– volume: 29
  start-page: 1224
  issue: 4
  year: 2009
  end-page: 1234
  article-title: Genetically determined interaction between the dopamine transporter and the D2 receptor on prefronto‐striatal activity and volume in humans
  publication-title: J Neurosci
– volume: 17
  start-page: 184
  issue: 1
  year: 2002
  end-page: 200
  article-title: The feasibility of a common stereotactic space for children and adults in fMRI studies of development
  publication-title: Neuroimage
– volume: 1
  start-page: 152
  issue: 2
  year: 2001
  end-page: 156
  article-title: The VNTR polymorphism of the human dopamine transporter (DAT1) gene affects gene expression
  publication-title: Pharmacogenomics J
– volume: 67
  start-page: 53
  issue: 1
  year: 2002
  end-page: 83
  article-title: Dopamine and the regulation of cognition and attention
  publication-title: Prog Neurobiol
– year: 1998
– volume: 11
  start-page: 805
  issue: 6 Pt 1
  year: 2000
  end-page: 821
  article-title: Voxel‐based morphometry—The methods
  publication-title: Neuroimage
– volume: 47
  start-page: 61
  issue: 1
  year: 2008
  end-page: 67
  article-title: Dopamine transporter genotype conveys familial risk of attention‐deficit/hyperactivity disorder through striatal activation
  publication-title: J Am Acad Child Adolesc Psychiatry
– volume: 8
  start-page: 339
  issue: 4
  year: 1993
  end-page: 347
  article-title: Attention deficit‐hyperactivity disorder and asymmetry of the caudate nucleus
  publication-title: J Child Neurol
– volume: 151
  start-page: 1430
  issue: 10
  year: 1994
  end-page: 1436
  article-title: Increase in caudate nuclei volumes of first‐episode schizophrenic patients taking antipsychotic drugs
  publication-title: Am J Psychiatry
– volume: 126
  start-page: 51
  issue: 1
  year: 2009
  end-page: 90
  article-title: Candidate gene studies of ADHD: A meta‐analytic review
  publication-title: Hum Genet
– volume: 22
  start-page: 133
  issue: 2
  year: 2000
  end-page: 139
  article-title: Genotype influences in vivo dopamine transporter availability in human striatum
  publication-title: Neuropsychopharmacology
– volume: 56
  start-page: 993
  issue: 4
  year: 1995
  end-page: 998
  article-title: Association of attention‐deficit disorder and the dopamine transporter gene
  publication-title: Am J Hum Genet
– volume: 43
  start-page: 181
  issue: 3
  year: 2002
  end-page: 187
  article-title: Relationship between blockade of dopamine transporters by oral methylphenidate and the increases in extracellular dopamine: Therapeutic implications
  publication-title: Synapse
– volume: 345
  start-page: 456
  issue: 8947
  year: 1995
  end-page: 457
  article-title: Caudate nuclei volumes in schizophrenic patients treated with typical antipsychotics or clozapine
  publication-title: Lancet
– volume: 42
  start-page: 986
  issue: 8
  year: 2003
  end-page: 993
  article-title: Functional effects of the DAT1 polymorphism on EEG measures in ADHD
  publication-title: J Am Acad Child Adolesc Psychiatry
– volume: 6
  start-page: 55
  year: 2005
  article-title: The variable number of tandem repeats element in DAT1 regulates in vitro dopamine transporter density
  publication-title: BMC Genet
– volume: 288
  start-page: 1740
  issue: 14
  year: 2002
  end-page: 1748
  article-title: Developmental trajectories of brain volume abnormalities in children and adolescents with attention‐deficit/hyperactivity disorder
  publication-title: JAMA
– volume: 46
  start-page: 745
  issue: 5
  year: 2005
  end-page: 751
  article-title: Increased dopamine transporter availability associated with the 9‐repeat allele of the SLC6A3 gene
  publication-title: J Nucl Med
– volume: 8
  start-page: 51
  year: 2008
  article-title: Structural brain change in attention deficit hyperactivity disorder identified by meta‐analysis
  publication-title: BMC Psychiatry
– volume: 45
  start-page: S173
  issue: 1 Suppl
  year: 2009
  end-page: S186
  article-title: Bayesian analysis of neuroimaging data in FSL
  publication-title: Neuroimage
– volume: 63
  start-page: 1767
  issue: 6
  year: 1998
  end-page: 1776
  article-title: Association and linkage of the dopamine transporter gene and attention‐deficit hyperactivity disorder in children: Heterogeneity owing to diagnostic subtype and severity
  publication-title: Am J Hum Genet
– volume: 1
  start-page: 105
  issue: 1
  year: 2005
  end-page: 113
  article-title: Voxel‐based morphometry of the human brain: Methods and applications
  publication-title: Curr Med Imaging Rev
– volume: 54
  start-page: 963
  issue: 8
  year: 1997
  end-page: 968
  article-title: Magnetic resonance imaging measurement of the caudate nucleus in adolescents with attention‐deficit hyperactivity disorder and its relationship with neuropsychological and behavioral measures
  publication-title: Arch Neurol
– volume: 64
  start-page: 226
  issue: 3
  year: 2008
  end-page: 234
  article-title: Epistasis between dopamine regulating genes identifies a nonlinear response of the human hippocampus during memory tasks
  publication-title: Biol Psychiatry
– volume: 7
  start-page: 152
  issue: 3
  year: 2006
  end-page: 157
  article-title: Striatal dopamine transporter availability and DAT‐1 gene in adults with ADHD: No higher DAT availability in patients with homozygosity for the 10‐repeat allele
  publication-title: World J Biol Psychiatry
– volume: 57
  start-page: 1293
  issue: 11
  year: 2005
  end-page: 1300
  article-title: In vivo neuroreceptor imaging in attention‐deficit/hyperactivity disorder: A focus on the dopamine transporter
  publication-title: Biol Psychiatry
– volume: 12
  start-page: 538
  issue: 5
  year: 2000
  end-page: 549
  article-title: Statistical parametric mapping: Assessment of application in children
  publication-title: Neuroimage
– volume: 50
  start-page: 45
  issue: 1
  year: 2009
  end-page: 52
  article-title: Striatal dopamine transporter availability associated with polymorphisms in the dopamine transporter gene SLC6A3
  publication-title: J Nucl Med
– volume: 14
  start-page: 261
  issue: 4
  year: 2008
  end-page: 267
  article-title: Cognitive neuroscience of attention deficit hyperactivity disorder: Current status and working hypotheses
  publication-title: Dev Disabil Res Rev
– volume: 133B
  start-page: 68
  issue: 1
  year: 2005
  end-page: 73
  article-title: Quantitative trait locus analysis of candidate gene alleles associated with attention deficit hyperactivity disorder (ADHD) in five genes: DRD4, DAT1, DRD5, SNAP‐25, and 5HT1B
  publication-title: Am J Med Genet Part B
– volume: 57
  start-page: 1397
  issue: 11
  year: 2005
  end-page: 1409
  article-title: The dopamine transporter and attention‐deficit/hyperactivity disorder
  publication-title: Biol Psychiatry
– volume: 24
  start-page: 553
  issue: 5
  year: 2001
  end-page: 560
  article-title: The variable number of tandem repeats polymorphism of the dopamine transporter gene is not associated with significant change in dopamine transporter phenotype in humans
  publication-title: Neuropsychopharmacology
– volume: 39
  start-page: 477
  issue: 4
  year: 2000
  end-page: 484
  article-title: Using MRI to examine brain‐behavior relationships in males with attention deficit disorder with hyperactivity
  publication-title: J Am Acad Child Adolesc Psychiatry
– volume: 48
  start-page: 589
  issue: 3
  year: 1997
  end-page: 601
  article-title: Volumetric MRI analysis comparing subjects having attention‐deficit hyperactivity disorder with normal controls
  publication-title: Neurology
– volume: 17
  start-page: 97
  issue: 2
  year: 2002
  end-page: 105
  article-title: Statistical analyses of structural magnetic resonance imaging of the head of the caudate nucleus in Colombian children with attention‐deficit hyperactivity disorder
  publication-title: J Child Neurol
– volume: 36
  start-page: 374
  issue: 3
  year: 1997
  end-page: 383
  article-title: Implication of right frontostriatal circuitry in response inhibition and attention‐deficit/hyperactivity disorder
  publication-title: J Am Acad Child Adolesc Psychiatry
– volume: 10
  start-page: 678
  issue: 7
  year: 2005
  end-page: 685
  article-title: Differential effects of DRD4 and DAT1 genotype on fronto‐striatal gray matter volumes in a sample of subjects with attention deficit hyperactivity disorder, their unaffected siblings, and controls
  publication-title: Mol Psychiatry
– volume: 61
  start-page: 1361
  issue: 12
  year: 2007
  end-page: 1369
  article-title: Meta‐analysis of structural imaging findings in attention‐deficit/hyperactivity disorder
  publication-title: Biol Psychiatry
– volume: 57
  start-page: 1273
  issue: 11
  year: 2005
  end-page: 1284
  article-title: Functional neuroimaging of attention‐deficit/hyperactivity disorder: A review and suggested future directions
  publication-title: Biol Psychiatry
– volume: 157
  start-page: 1700
  issue: 10
  year: 2000
  end-page: 1703
  article-title: Prediction of dopamine transporter binding availability by genotype: A preliminary report
  publication-title: Am J Psychiatry
– volume: 7
  start-page: 44
  issue: 1
  year: 2002
  end-page: 55
  article-title: Polymorphisms in the 3′‐untranslated region of human and monkey dopamine transporter genes affect reporter gene expression
  publication-title: Mol Psychiatry
– volume: 120
  start-page: 257
  issue: Pt 2
  year: 1997
  end-page: 269
  article-title: Genetic variability of human brain size and cortical gyral patterns
  publication-title: Brain
– volume: 64
  start-page: 921
  issue: 8
  year: 2007
  end-page: 931
  article-title: Polymorphisms of the dopamine D4 receptor, clinical outcome, and cortical structure in attention‐deficit/hyperactivity disorder
  publication-title: Arch Gen Psychiatry
– volume: 10
  start-page: 686
  issue: 7
  year: 2005
  end-page: 698
  article-title: Association of the dopamine transporter (DAT1) 10/10‐repeat genotype with ADHD symptoms and response inhibition in a general population sample
  publication-title: Mol Psychiatry
– volume: 23
  start-page: S208
  issue: Suppl 1
  year: 2004
  end-page: S219
  article-title: Advances in functional and structural MR image analysis and implementation as FSL
  publication-title: Neuroimage
– volume: 15
  start-page: 95
  issue: 1
  year: 2005
  end-page: 101
  article-title: The homozygosity for 10‐repeat allele at dopamine transporter gene and dopamine transporter density in Korean children with attention deficit hyperactivity disorder: Relating to treatment response to methylphenidate
  publication-title: Eur Neuropsychopharmacol
– volume: 151
  start-page: 1791
  issue: 12
  year: 1994
  end-page: 1796
  article-title: Quantitative morphology of the caudate nucleus in attention deficit hyperactivity disorder
  publication-title: Am J Psychiatry
– year: 1999
– ident: e_1_2_6_55_1
  doi: 10.1002/ajmg.b.30453
– ident: e_1_2_6_51_1
  doi: 10.1186/1471-2156-6-55
– ident: e_1_2_6_8_1
  doi: 10.1097/00004583-199703000-00016
– ident: e_1_2_6_25_1
  doi: 10.1016/S0893-133X(99)00099-8
– ident: e_1_2_6_13_1
  doi: 10.1016/S0140-6736(95)90441-7
– ident: e_1_2_6_52_1
  doi: 10.1002/syn.10038
– ident: e_1_2_6_7_1
  doi: 10.1016/j.biopsych.2005.01.034
– ident: e_1_2_6_37_1
  doi: 10.1006/nimg.2000.0651
– ident: e_1_2_6_5_1
  doi: 10.1523/JNEUROSCI.4858-08.2009
– ident: e_1_2_6_3_1
  doi: 10.1093/brain/120.2.257
– ident: e_1_2_6_30_1
  doi: 10.1016/j.biopsych.2004.10.011
– ident: e_1_2_6_44_1
  doi: 10.1001/archpsyc.64.8.921
– ident: e_1_2_6_14_1
  doi: 10.1016/j.euroneuro.2004.06.004
– ident: e_1_2_6_21_1
  doi: 10.1186/1471-244X-8-51
– ident: e_1_2_6_16_1
  doi: 10.1038/sj.mp.4001641
– ident: e_1_2_6_41_1
  doi: 10.1016/j.biopsych.2004.11.019
– ident: e_1_2_6_38_1
  doi: 10.1016/S0301-0082(02)00011-4
– ident: e_1_2_6_43_1
  doi: 10.1212/01.wnl.0000237385.84037.3c
– ident: e_1_2_6_12_1
  doi: 10.1176/ajp.151.10.1430
– ident: e_1_2_6_18_1
  doi: 10.1038/sj.mp.4001649
– ident: e_1_2_6_39_1
  doi: 10.1177/088307380201700202
– ident: e_1_2_6_54_1
  doi: 10.1016/j.neuroimage.2008.10.055
– ident: e_1_2_6_47_1
  doi: 10.1002/ddrr.40
– ident: e_1_2_6_35_1
  doi: 10.1002/ajmg.b.30107
– ident: e_1_2_6_46_1
  doi: 10.1016/j.biopsych.2005.03.036
– ident: e_1_2_6_23_1
  doi: 10.1038/sj.tpj.6500026
– ident: e_1_2_6_49_1
  doi: 10.2967/jnumed.108.053652
– volume-title: Behavior assessment system for children
  year: 1998
  ident: e_1_2_6_40_1
  contributor:
    fullname: Reynolds CR
– ident: e_1_2_6_24_1
  doi: 10.1007/s00439-009-0694-x
– ident: e_1_2_6_45_1
  doi: 10.1016/j.neuroimage.2004.07.051
– volume-title: ADHD‐Rating Scales DSM‐IV for parents and teachers
  year: 1998
  ident: e_1_2_6_17_1
  contributor:
    fullname: DuPaul GJ
– ident: e_1_2_6_36_1
  doi: 10.1038/sj.mp.4000921
– ident: e_1_2_6_2_1
  doi: 10.1006/nimg.2000.0582
– ident: e_1_2_6_42_1
  doi: 10.1097/00004583-200004000-00017
– ident: e_1_2_6_33_1
  doi: 10.2174/1573405054038726
– ident: e_1_2_6_9_1
  doi: 10.1176/ajp.151.12.1791
– ident: e_1_2_6_32_1
  doi: 10.1001/archneur.1997.00550200027006
– ident: e_1_2_6_26_1
  doi: 10.1177/088307389300800409
– ident: e_1_2_6_28_1
  doi: 10.1080/15622970500518444
– ident: e_1_2_6_29_1
  doi: 10.1097/01.CHI.0000046890.27264.88
– ident: e_1_2_6_10_1
  doi: 10.1001/archpsyc.1996.01830070053009
– ident: e_1_2_6_34_1
  doi: 10.1002/ajmg.b.10948
– ident: e_1_2_6_11_1
  doi: 10.1001/jama.288.14.1740
– ident: e_1_2_6_6_1
  doi: 10.1006/nimg.2002.1174
– volume-title: The Human brain: Surface blood supply and three‐dimensional section anatomy
  year: 1999
  ident: e_1_2_6_20_1
  doi: 10.1007/978-3-7091-6792-2
  contributor:
    fullname: Duvernoy HM
– volume: 46
  start-page: 745
  issue: 5
  year: 2005
  ident: e_1_2_6_50_1
  article-title: Increased dopamine transporter availability associated with the 9‐repeat allele of the SLC6A3 gene
  publication-title: J Nucl Med
  contributor:
    fullname: van Dyck CH
– ident: e_1_2_6_31_1
  doi: 10.1016/S0893-133X(00)00216-5
– ident: e_1_2_6_53_1
  doi: 10.1086/302132
– ident: e_1_2_6_4_1
  doi: 10.1016/j.biopsych.2008.02.001
– volume: 56
  start-page: 993
  issue: 4
  year: 1995
  ident: e_1_2_6_15_1
  article-title: Association of attention‐deficit disorder and the dopamine transporter gene
  publication-title: Am J Hum Genet
  contributor:
    fullname: Cook EH
– ident: e_1_2_6_27_1
  doi: 10.1176/appi.ajp.157.10.1700
– ident: e_1_2_6_19_1
  doi: 10.1097/chi.0b013e31815a5f17
– ident: e_1_2_6_48_1
  doi: 10.1016/j.biopsych.2006.06.011
– ident: e_1_2_6_22_1
  doi: 10.1212/WNL.48.3.589
SSID ssj0030577
Score 2.157173
Snippet Polymorphism of the dopamine transporter genotype (DAT1) confers a small but significant susceptibility to attention deficit hyperactivity disorder (ADHD). We...
Abstract Polymorphism of the dopamine transporter genotype (DAT1) confers a small but significant susceptibility to attention deficit hyperactivity disorder...
SourceID pubmedcentral
proquest
crossref
pubmed
pascalfrancis
wiley
istex
SourceType Open Access Repository
Aggregation Database
Index Database
Publisher
StartPage 28
SubjectTerms Adolescent
Attention Deficit Disorder with Hyperactivity - genetics
Attention Deficit Disorder with Hyperactivity - pathology
Attention deficit hyperactivity disorder
Biological and medical sciences
brain
Brain Mapping
Case-Control Studies
Caudate Nucleus - pathology
Child
Children
Demography
Dopamine Plasma Membrane Transport Proteins - genetics
Dopamine transporter
Female
Genotype
Head
Hemispheric laterality
Humans
Intelligence
Male
Medical genetics
Medical sciences
Neostriatum
Organ Size
polymorphism
striatal
structure
VNTR
Title Effect of dopamine transporter genotype on caudate volume in childhood ADHD and controls
URI https://api.istex.fr/ark:/67375/WNG-V2HZTR60-N/fulltext.pdf
https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fajmg.b.31132
https://www.ncbi.nlm.nih.gov/pubmed/20957668
https://search.proquest.com/docview/1017971054
https://search.proquest.com/docview/821198051
https://pubmed.ncbi.nlm.nih.gov/PMC3010298
Volume 156B
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3db9MwED-hIRAvA8ZX-JiMBDyRrk2c2HmsGFs1aX2YNqh4sezYHmNaOvVDAv567uw0W_mSQOpDlJ6b5HI-_-58_R3AK-EQs1a5SfvGypRnXKayov4meiC8rGpbulDlOy5HJ_xgUkzahBv9FybyQ3QJN5oZwV_TBNdmvnNFGqq_XJz2DMacGE-hCyYuPcJERx17FFpyaLxIJGMpl3zQ1r3j8J3rg9dWpJuk3K9UIannqCQfu1v8Dn7-WkV5Hd2G5WnvLqjVg8WqlPPecmF69fefOB___8nvwWaLXNkwmtp9uOGaLbgVe1l-24Lbh-0u_QOYREpkNvXMYkx-gSfZoiNRnzHihaXUL5s2rNZLyjmw6CXZGZ5ZkS2z4e5ol-nGsraefv4QTvbeH78bpW0Hh7QuMJZLbZkb49AFYJRq0AbKOqsrogzMTe4IylW2b7ixXmiENTkuo4VFuI8HlvvS2vwRbDTTxj0BhrhK-rzmzvkBF4ZXmUcJ3-de86IQNoHXq7eoLiNRh4qUzJkihSmjgsISeBNecSekZ-dU3CYK9XG8rz5ko0_HR2VfjRPYXrOBbkCWC4n3ir_0cmUUCuckbbToxk2XcxXcHEK3gifA_iAjiVpPoktM4HG0o6sLIOwVZSkTEGsW1gkQJfj6N83Z50ANnhNFYIUj3wYD-qsm1PDgcD8cPf038WdwJ2bW6fMcNhazpXuB0GxhtsME_AG23DOn
link.rule.ids 230,315,786,790,891,1382,27955,27956,46327,46751
linkProvider Wiley-Blackwell
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Zb9NAEB5BK44XjnKZoywS8ITTxF7b68eI0JrS5KFKIeJl8Xp3oVR1UA4J-PXM7DpuwyUhpDxYzmwSj2dmvxlPvgF4mhnErHmswq7SIuQRF6HIab5J2cusyCudGtflO0qLI74_SSbNnFP6L4znh2gLbuQZLl6Tg1NBeueMNbT8fPqxozDpxITqImyixyfkmYPDlj8KbdmNXiSasZAL3ms633H9zvnVa3vSJqn3K_VIlnNUk_XzLX4HQH_tozyPb90GtXsdPqwuzfelnHSWC9Wpvv_E-vgf134DrjXglfW9td2EC6begkt-nOW3Lbg8bB7U34KJZ0VmU8s0puWneJItWh71GSNqWKr-smnNqnJJZQfmAyU7xjMrvmXWHxQDVtaaNS3189twtPtq_LIImyEOYZVgOhfqNFbKYBTARFWhGaRVVOXEGhir2BCay3VXcaVtViKyiXEnTTQifjzQ3KZax3dgo57W5h4whFbCxhU3xvZ4pngeWZSwXW5LniSZDuDZ6jbKL56rQ3pW5kiSwqSSTmEBPHf3uBUqZyfU35Yl8t1oT76Nivfjw7QrRwFsrxlBuyCKM4G_FT_pycoqJLolPWspazNdzqWLdIjeEh4A-4OMIHY9gVExgLvekM6-AJFvlqYigGzNxFoBYgVff6c-_uTYwWNiCcxx5QtnQX_VhOzvD_fc0f1_E38MV4rx8EAevB69eQBXfaGdXg9hYzFbmkeI1BZq23njD9zFN8c
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3db9MwED_BJiZe-Bhf4WMYCXgiXRs7ifNYUboyWIWmDSperDi2YUxLp7WVgL-eOzvNVr4kkPoQpecmuZzPvztffwfwNLeIWQuu4642MhaJkLEsqL9J2cudLCqTWV_lO85Gh2J3kk6ahBv9FybwQ7QJN5oZ3l_TBD81bvucNLT8cvKpozHmxHjqMqyLjCcUfA32W_ooNGXfeZFYxmIhRa8pfMfx2xdHryxJ66Tdr1QiWc5QSy60t_gd_vy1jPIivPXr0_A6qOWThbKU485irjvV959IH___0W_AtQa6sn6wtZtwydabcCU0s_y2CRt7zTb9LZgETmQ2dcxgUH6CJ9m8ZVE_Y0QMS7lfNq1ZVS4o6cCCm2RHeGbJtsz6g9GAlbVhTUH97DYcDl8dvBzFTQuHuEoxmItNxrW26AMwTNVoBFmVVAVxBnLNLWG5wnS10MblJeIajutoahDv44ERLjOG34G1elrbe8AQWEnHK2Gt64lciyJxKOG6wpUiTXMTwbPlW1SngalDBU7mRJHClFZeYRE896-4FSrPjqm6LU_Vh_GOep-MPh7sZ101jmBrxQbaAQnPJd4r_tKTpVEonJS001LWdrqYKe_nELulIgL2BxlJ3HoSfWIEd4MdnV8AcW-eZTKCfMXCWgHiBF_9pj767LnBOXEEFjjyhTegv2pC9Xf3dvzR_X8Tfwwb7wZD9fb1-M0DuBqy7PR5CGvzs4V9hDBtrrf8XPwBEA02dg
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Effect+of+Dopamine+Transporter+Genotype+on+Caudate+Volume+in+Childhood+ADHD+and+Controls&rft.jtitle=American+journal+of+medical+genetics.+Part+B%2C+Neuropsychiatric+genetics&rft.au=SHOOK%2C+Devon&rft.au=BRADY%2C+Colin&rft.au=LEE%2C+Philip+S&rft.au=KENEALY%2C+Laura&rft.date=2011-01-01&rft.pub=Wiley-Liss&rft.issn=1552-4841&rft.eissn=1552-485X&rft.volume=156&rft.issue=1&rft.spage=28&rft.epage=35&rft_id=info:doi/10.1002%2Fajmg.b.31132&rft.externalDBID=n%2Fa&rft.externalDocID=23784322
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1552-4841&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1552-4841&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1552-4841&client=summon