Draft genome sequences of two opportunistic pathogenic strains of Staphylococcus cohnii isolated from human patients

• Published in: Environmental microbiome Vol. 12; no. 1; pp. 49 - 9
• Main Authors: Mendoza-Olazarán, Soraya, Garcia-Mazcorro, José F, Morfín-Otero, Rayo, Villarreal-Treviño, Licet, Camacho-Ortiz, Adrián, Rodríguez-Noriega, Eduardo, Bocanegra-Ibarias, Paola, Maldonado-Garza, Héctor J, Dowd, Scot E, Garza-González, Elvira
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 31.08.2017; BioMed Central; BMC
• Subjects: Amino acid metabolism; Antibiotic resistance; Antibiotics; Bacteria; Bacteriology; Biofilm; Biofilms; Carbohydrates; Catheters; Chromosomes; Classification; Clinical strains; Coagulase-negative staphylococci; DNA sequencing; Drug resistance in microorganisms; Extended Genome Report; Fermentation; Genetic aspects; Genomes; Lactose; Medical equipment; Microscopy; Nucleotide sequencing; Phylogenetics; Physiological aspects; SCCmec; Short genome report; Staphylococcus; Staphylococcus cohnii; Staphylococcus infections; Virulence; Biofilm; Short genome report; Clinical strains; SCCmec; Staphylococcus cohnii; Coagulase-negative staphylococci
• ISSN: 1944-3277; 1944-3277; 2524-6372
• DOI: 10.1186/s40793-017-0263-1

Herein, we report the draft-genome sequences and annotation of two opportunistic pathogenic strains of isolated from humans. One strain (SC-57) was isolated from blood from a male patient in May 2006 and the other (SC-532) from a catheter from a male patient in June 2006. Similar to other genomes of species, most genes (42%) of both strains are involved in metabolism of amino acids and derivatives, carbohydrates and proteins. Eighty (4%) genes are involved in virulence, disease, and defense and both species show phenotypic low biofilm production and evidence of increased antibiotic resistance associated to biofilm production. From both isolates, a new Staphylococcal Cassette Chromosome was detected: class A, type 1. This is the first report of whole genome sequences of opportunistic isolated from human patients.