Persistent organohalogen contaminants in plasma from groups of humans with different occupations in Bangladesh

• Published in: Chemosphere (Oxford) Vol. 74; no. 3; pp. 453 - 459
• Main Authors: Zamir, R., Athanasiadou, M., Nahar, N., Mamun, M.I.R., Mosihuzzaman, M., Bergman, Å.
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 2009; Elsevier
• Subjects: Anticonvulsants - blood; Bangladesh; Biological and medical sciences; Blood; blood plasma; DDT; DDT (pesticide); DDTs; Dichlorodiphenyl Dichloroethylene; Environmental Monitoring; Environmental Pollutants - blood; Environmental pollutants toxicology; Female; General aspects; HCB; HCH (pesticide); HCHs; hexachlorobenzene; Humans; Hydrocarbons, Halogenated - blood; insecticide residues; Insecticides - blood; Lindane; Male; Medical sciences; Occupational Exposure - analysis; Occupations; Organic pollutants; PCBs; pesticide residues; Polychlorinated Biphenyls; Risk Assessment; Stereoisomerism; students; Toxicology; Bangladesh; Asia; DDTs; PCBs; Organic pollutants; HCB; Blood; HCHs; Human; Rate; Polychlorobiphenyls; HCH; Epidemiology; Blood plasma; Persistent organic pollutant; DDT; Chlorine Organic compounds; Public health
• ISSN: 0045-6535; 1879-1298; 1879-1298
• DOI: 10.1016/j.chemosphere.2008.09.043

The present study is aimed to assess persistent organic halogenated pollutants in humans living in Bangladesh. The results are compared to other similar studies in the region and globally. Human blood plasma were collected from groups of men and women with different occupations, i.e. being students, garment industry workers, employees at the Power Development Board (PDB), all groups in Dhaka, fishermen and fishermen wife’s from Dhaka and another group from Barisal district. The plasma was analysed for hexachlorobenzene (HCB), the hexachlorocyclohexane isomers, α-HCH, β-HCH, γ-HCH and δ-HCH, the DDT group of chemicals, chlordane compounds, trans-chlordane, cis-chlordane, oxychlordane, trans-nonachlor, trans-heptachlorepoxide, methoxychlor and mirex. The most abundant contaminant, in all groups studied, p, p′-DDE is dominating, with p, p′-DDT/∑DDT ratios indicating recent and ongoing DDT exposure. Among the other pesticides analysed β-HCH is the most abundant indicating the use of technical HCH products instead of Lindane (γ-HCH). While the ∑DDT is present in the low ppm range the β-HCH is detected in up to approx. 400 ppb, lipid basis. The β-HCH is most abundant in the groups of students. In contrast to the pesticides analysed very low concentrations of polychlorinated biphenyls (PCB) are present in all study groups, with e.g. CB-153 in the range of 5–30 ng g −1 fat. The concentrations of the DDT group of chemical differ significantly between fishermen and fishermen’s wives living and working in the Dhaka area versus those living and working in Barisal. Also, fishermen and their wives had significantly different concentrations of DDT compared to garment industry workers.